E681-0265 Screening compound: N-[5-(4-benzylpiperazine-1-carbonyl)pyridin-3-yl]-4-chlorobenzene-1-sulfonamide

E681-0265 Screening compound: N-[5-(4-benzylpiperazine-1-carbonyl)pyridin-3-yl]-4-chlorobenzene-1-sulfonamide
E681-0265 Screening compound: N-[5-(4-benzylpiperazine-1-carbonyl)pyridin-3-yl]-4-chlorobenzene-1-sulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E681-0265
N-[5-(4-benzylpiperazine-1-carbonyl)pyridin-3-yl]-4-chlorobenzene-1-sulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E681-0265

Molecular Formula

C23H23ClN4O3S (C23 H23 ClN4 O3 S)

Compound Name

N-[5-(4-benzylpiperazine-1-carbonyl)pyridin-3-yl]-4-chlorobenzene-1-sulfonamide

IUPAC name

N-[5-(4-benzylpiperazine-1-carbonyl)pyridin-3-yl]-4-chlorobenzene-1-sulfonamide

SMILES

O=C(c1cc(NS(c(cc2)ccc2Cl)(=O)=O)cnc1)N1CCN(Cc2ccccc2)CC1

InChI

InChI=1S/C23H23ClN4O3S/c24-20-6-8-22(9-7-20)32(30,31)26-21-14-19(15-25-16-21)23(29)28-12-10-27(11-13-28)17-18-4-2-1-3-5-18/h1-9,14-16,26H,10-13,17H2

InChI Key

RZRYXFCWWIMOPR-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD06737694

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

470.98

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.204

Distribution Coefficient, logD

3.140

Water Solubility, LogSw

-3.71

Polar Surface Area

70.684

Acid Dissociation Constant (pKa)

8.32

Base Dissociation Constant (pKb)

5.96

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

21.70

E681-0265 in Drug Discovery

Included in Screening Libraries

CNS Targets (44014 compounds)

GPCR Targeted Library (31838 compounds)

PI3K-Targeted Library (17255 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • GPCR
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with E681-0265 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E681-0265?
Check Price and Availability of E681-0265, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E681-0265 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E681-0265
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E681-0265
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E681-0265 available by request