E683-0362 Screening compound: N-{2-[(3-chlorophenyl)amino]-4-methylquinolin-6-yl}-2-(thiophen-2-yl)quinoline-4-carboxamide

E683-0362 Screening compound: N-{2-[(3-chlorophenyl)amino]-4-methylquinolin-6-yl}-2-(thiophen-2-yl)quinoline-4-carboxamide
E683-0362 Screening compound: N-{2-[(3-chlorophenyl)amino]-4-methylquinolin-6-yl}-2-(thiophen-2-yl)quinoline-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E683-0362
N-{2-[(3-chlorophenyl)amino]-4-methylquinolin-6-yl}-2-(thiophen-2-yl)quinoline-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E683-0362

Molecular Formula

C30H21ClN4OS (C30 H21 ClN4 OS)

Compound Name

N-{2-[(3-chlorophenyl)amino]-4-methylquinolin-6-yl}-2-(thiophen-2-yl)quinoline-4-carboxamide

IUPAC name

N-{2-[(3-chlorophenyl)amino]-4-methylquinolin-6-yl}-2-(thiophen-2-yl)quinoline-4-carboxamide

SMILES

Cc(c1c2)cc(Nc3cccc(Cl)c3)nc1ccc2NC(c1cc(-c2cccs2)nc2ccccc12)=O

InChI

InChI=1S/C30H21ClN4OS/c1-18-14-29(32-20-7-4-6-19(31)15-20)35-26-12-11-21(16-23(18)26)33-30(36)24-17-27(28-10-5-13-37-28)34-25-9-3-2-8-22(24)25/h2-17H,1H3,(H,32,35)(H,33,36)

InChI Key

XOMPIQCUNMTILT-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14909859

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

521.04

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

8.740

Distribution Coefficient, logD

8.740

Water Solubility, LogSw

-6.38

Polar Surface Area

50.217

Acid Dissociation Constant (pKa)

11.53

Base Dissociation Constant (pKb)

4.50

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

3.30

E683-0362 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Lipid Metabolism Library (9174 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cardiovascular
  • Metabolic

References: we are preparing a list of scientific research reports with E683-0362 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E683-0362?
Check Price and Availability of E683-0362, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E683-0362 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E683-0362
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E683-0362
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E683-0362 available by request