E699-1378 Screening compound: 1-cyclobutanecarbonyl-5-[(4-cyclohexylpiperazin-1-yl)sulfonyl]-2-methyl-2,3-dihydro-1H-indole

E699-1378 Screening compound: 1-cyclobutanecarbonyl-5-[(4-cyclohexylpiperazin-1-yl)sulfonyl]-2-methyl-2,3-dihydro-1H-indole
E699-1378 Screening compound: 1-cyclobutanecarbonyl-5-[(4-cyclohexylpiperazin-1-yl)sulfonyl]-2-methyl-2,3-dihydro-1H-indole alternative view

Chemical Structure Depiction of ChemDiv screening compound E699-1378
1-cyclobutanecarbonyl-5-[(4-cyclohexylpiperazin-1-yl)sulfonyl]-2-methyl-2,3-dihydro-1H-indole

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E699-1378

Molecular Formula

C24H35N3O3S (C24 H35 N3 O3 S)

Compound Name

1-cyclobutanecarbonyl-5-[(4-cyclohexylpiperazin-1-yl)sulfonyl]-2-methyl-2,3-dihydro-1H-indole

IUPAC name

1-cyclobutanecarbonyl-5-[(4-cyclohexylpiperazin-1-yl)sulfonyl]-2-methyl-23-dihydro-1H-indole

SMILES

CC(C1)N(C(C2CCC2)=O)c(cc2)c1cc2S(N(CC1)CCN1C1CCCCC1)(=O)=O

MDL Number (MFCD)

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

445.63

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.426

Distribution Coefficient, logD

3.347

Water Solubility, LogSw

-3.77

Polar Surface Area

50.184

Acid Dissociation Constant (pKa)

22.36

Base Dissociation Constant (pKb)

6.70

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

70.80

E699-1378 in Drug Discovery

Included in Screening Libraries

GPCR Targeted Library (31838 compounds)

Purinergic Library (3321 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Nervous system
  • Cardiovascular
  • Metabolic
Targets:
  • GPCR
  • GPCR
  • Ion Channels
Mechanism of action:
  • Receptor's ligands
  • Receptor's ligands

References: we are preparing a list of scientific research reports with E699-1378 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E699-1378?
Check Price and Availability of E699-1378, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E699-1378 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E699-1378
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E699-1378
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E699-1378 available by request