E711-0237 Screening compound: 1-[3-(4-chlorophenyl)-5H,6H,7H,8H,9H-imidazo[1,5-a]azepine-1-carbonyl]-4-(2-fluorophenyl)piperazine

E711-0237 Screening compound: 1-[3-(4-chlorophenyl)-5H,6H,7H,8H,9H-imidazo[1,5-a]azepine-1-carbonyl]-4-(2-fluorophenyl)piperazine
E711-0237 Screening compound: 1-[3-(4-chlorophenyl)-5H,6H,7H,8H,9H-imidazo[1,5-a]azepine-1-carbonyl]-4-(2-fluorophenyl)piperazine alternative view

Chemical Structure Depiction of ChemDiv screening compound E711-0237
1-[3-(4-chlorophenyl)-5H,6H,7H,8H,9H-imidazo[1,5-a]azepine-1-carbonyl]-4-(2-fluorophenyl)piperazine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E711-0237

Molecular Formula

C25H26ClFN4O (C25 H26 ClFN4 O)

Compound Name

1-[3-(4-chlorophenyl)-5H,6H,7H,8H,9H-imidazo[1,5-a]azepine-1-carbonyl]-4-(2-fluorophenyl)piperazine

IUPAC name

1-[3-(4-chlorophenyl)-5H6H7H8H9H-imidazo[15-a]azepine-1-carbonyl]-4-(2-fluorophenyl)piperazine

SMILES

O=C(c1c(CCCCC2)n2c(-c(cc2)ccc2Cl)n1)N(CC1)CCN1c(cccc1)c1F

InChI

InChI=1S/C25H26ClFN4O/c26-19-11-9-18(10-12-19)24-28-23(22-8-2-1-5-13-31(22)24)25(32)30-16-14-29(15-17-30)21-7-4-3-6-20(21)27/h3-4,6-7,9-12H,1-2,5,8,13-17H2

InChI Key

YCJPTSQLRNWCTN-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14911192

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

452.96

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

5.539

Distribution Coefficient, logD

5.539

Water Solubility, LogSw

-5.99

Polar Surface Area

30.687

Acid Dissociation Constant (pKa)

23.28

Base Dissociation Constant (pKb)

2.17

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

36.00

E711-0237 in Drug Discovery

Included in Screening Libraries

CNS BBB Library (22607 compounds)

Protein-Protein Interaction Library (218420 compounds)

Selective Target Activity Profiling Library (14702 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Recognition Elements PPI Library (24135 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with E711-0237 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E711-0237?
Check Price and Availability of E711-0237, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E711-0237 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E711-0237
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E711-0237
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E711-0237 available by request