E734-0183 Screening compound: N-[3-(dimethylamino)-4-methylphenyl]-7-methyl-2,3-dioxo-1,2,3,4-tetrahydroquinoxaline-6-sulfonamide

E734-0183 Screening compound: N-[3-(dimethylamino)-4-methylphenyl]-7-methyl-2,3-dioxo-1,2,3,4-tetrahydroquinoxaline-6-sulfonamide
E734-0183 Screening compound: N-[3-(dimethylamino)-4-methylphenyl]-7-methyl-2,3-dioxo-1,2,3,4-tetrahydroquinoxaline-6-sulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E734-0183
N-[3-(dimethylamino)-4-methylphenyl]-7-methyl-2,3-dioxo-1,2,3,4-tetrahydroquinoxaline-6-sulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E734-0183

Molecular Formula

C18H20N4O4S (C18 H20 N4 O4 S)

Compound Name

N-[3-(dimethylamino)-4-methylphenyl]-7-methyl-2,3-dioxo-1,2,3,4-tetrahydroquinoxaline-6-sulfonamide

IUPAC name

N-[3-(dimethylamino)-4-methylphenyl]-7-methyl-23-dioxo-1234-tetrahydroquinoxaline-6-sulfonamide

SMILES

Cc(ccc(NS(c(cc1NC2=O)c(C)cc1NC2=O)(=O)=O)c1)c1N(C)C

InChI

InChI=1S/C18H20N4O4S/c1-10-5-6-12(8-15(10)22(3)4)21-27(25,26)16-9-14-13(7-11(16)2)19-17(23)18(24)20-14/h5-9,21H,1-4H3,(H,19,23)(H,20,24)

InChI Key

UDCDZHCSEAVDOI-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14913496

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

388.45

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

3.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.326

Distribution Coefficient, logD

1.874

Water Solubility, LogSw

-2.93

Polar Surface Area

93.226

Acid Dissociation Constant (pKa)

7.14

Base Dissociation Constant (pKb)

4.30

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

22.20

E734-0183 in Drug Discovery

Included in Screening Libraries

Anti-Inflammatory Library (24602 compounds)

Anticancer Library (62698 compounds)

Antiviral Annotated Library (21441 compounds)

Antiviral Library (67538 compounds)

DGK Inhibitors Library (10558 compounds)

Purinergic Library (3321 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Neuropeptide S Library (2850 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Immune system
  • Cancer
  • Antiviral
  • Infections
  • Immune system
  • Cancer
  • Digestive system
  • Hemic and lymphatic
  • Skin
  • Metabolic
  • Immune system
  • Nervous system
  • Cardiovascular
  • Metabolic
  • Digestive system
  • Nervous system
Targets:
  • Kinases
  • GPCR
  • Ion Channels
  • GPCR
Mechanism of action:
  • Receptor's ligands
  • Receptor's ligands

References: we are preparing a list of scientific research reports with E734-0183 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E734-0183?
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What is the minimum amount of E734-0183 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E734-0183
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E734-0183
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E734-0183 available by request