E756-0264 Screening compound: 1-[5-fluoro-1-methyl-2-(4-phenylpiperazine-1-carbonyl)-1H-indol-3-yl]pyrrolidin-2-one

E756-0264 Screening compound: 1-[5-fluoro-1-methyl-2-(4-phenylpiperazine-1-carbonyl)-1H-indol-3-yl]pyrrolidin-2-one
E756-0264 Screening compound: 1-[5-fluoro-1-methyl-2-(4-phenylpiperazine-1-carbonyl)-1H-indol-3-yl]pyrrolidin-2-one alternative view

Chemical Structure Depiction of ChemDiv screening compound E756-0264
1-[5-fluoro-1-methyl-2-(4-phenylpiperazine-1-carbonyl)-1H-indol-3-yl]pyrrolidin-2-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E756-0264

Molecular Formula

C24H25FN4O2 (C24 H25 FN4 O2)

Compound Name

1-[5-fluoro-1-methyl-2-(4-phenylpiperazine-1-carbonyl)-1H-indol-3-yl]pyrrolidin-2-one

IUPAC name

1-[5-fluoro-1-methyl-2-(4-phenylpiperazine-1-carbonyl)-1H-indol-3-yl]pyrrolidin-2-one

SMILES

Cn(c(cc1)c2cc1F)c(C(N(CC1)CCN1c1ccccc1)=O)c2N(CCC1)C1=O

InChI

InChI=1S/C24H25FN4O2/c1-26-20-10-9-17(25)16-19(20)22(29-11-5-8-21(29)30)23(26)24(31)28-14-12-27(13-15-28)18-6-3-2-4-7-18/h2-4,6-7,9-10,16H,5,8,11-15H2,1H3

InChI Key

WJQZMFSVKBSOLV-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14916128

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

420.49

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.339

Distribution Coefficient, logD

3.339

Water Solubility, LogSw

-3.69

Polar Surface Area

37.673

Acid Dissociation Constant (pKa)

14.51

Base Dissociation Constant (pKb)

5.75

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

33.30

E756-0264 in Drug Discovery

Included in Screening Libraries

Protein Kinases Inhibitors Library (36801 compounds)

Anti-HIV1 Library (19540 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
  • Antiviral
  • Infections
  • Immune system
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with E756-0264 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E756-0264?
Check Price and Availability of E756-0264, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E756-0264 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E756-0264
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E756-0264
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E756-0264 available by request