E757-0043 Screening compound: N-cyclopentyl-4-({5,8-dioxo-hexahydro-1H-[1,3]thiazolo[3,4-a]pyrazin-7-yl}methyl)benzamide

E757-0043 Screening compound: N-cyclopentyl-4-({5,8-dioxo-hexahydro-1H-[1,3]thiazolo[3,4-a]pyrazin-7-yl}methyl)benzamide
E757-0043 Screening compound: N-cyclopentyl-4-({5,8-dioxo-hexahydro-1H-[1,3]thiazolo[3,4-a]pyrazin-7-yl}methyl)benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E757-0043
N-cyclopentyl-4-({5,8-dioxo-hexahydro-1H-[1,3]thiazolo[3,4-a]pyrazin-7-yl}methyl)benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E757-0043

Molecular Formula

C19H23N3O3S (C19 H23 N3 O3 S)

Compound Name

N-cyclopentyl-4-({5,8-dioxo-hexahydro-1H-[1,3]thiazolo[3,4-a]pyrazin-7-yl}methyl)benzamide

IUPAC name

N-cyclopentyl-4-({58-dioxo-hexahydro-1H-[13]thiazolo[34-a]pyrazin-7-yl}methyl)benzamide

SMILES

O=C(c1ccc(CN(CC(N2C3CSC2)=O)C3=O)cc1)NC1CCCC1

InChI

InChI=1S/C19H23N3O3S/c23-17-10-21(19(25)16-11-26-12-22(16)17)9-13-5-7-14(8-6-13)18(24)20-15-3-1-2-4-15/h5-8,15-16H,1-4,9-12H2,(H,20,24)/t16-/m1/s1

InChI Key

LNAZDFLLJMGJDR-MRXNPFEDSA-N

MDL Number (MFCD)

MFCD14916411

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

373.48

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

1.299

Distribution Coefficient, logD

1.299

Water Solubility, LogSw

-2.31

Polar Surface Area

58.162

Acid Dissociation Constant (pKa)

14.73

Base Dissociation Constant (pKb)

-1.65

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

52.60

E757-0043 in Drug Discovery

Included in Screening Libraries

GPCR Targeted Library (31838 compounds)

Soluble Diversity Library (15920 compounds)

Targeted Diversity Library (40567 compounds)

Anti-HIV1 Library (19540 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Antiviral
  • Infections
  • Immune system
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with E757-0043 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E757-0043?
Check Price and Availability of E757-0043, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E757-0043 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E757-0043
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E757-0043
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E757-0043 available by request