E760-0912 Screening compound: 1-(4-{2-ethyl-3H-imidazo[4,5-b]pyridin-3-yl}benzoyl)azepane

E760-0912 Screening compound: 1-(4-{2-ethyl-3H-imidazo[4,5-b]pyridin-3-yl}benzoyl)azepane
E760-0912 Screening compound: 1-(4-{2-ethyl-3H-imidazo[4,5-b]pyridin-3-yl}benzoyl)azepane alternative view

Chemical Structure Depiction of ChemDiv screening compound E760-0912
1-(4-{2-ethyl-3H-imidazo[4,5-b]pyridin-3-yl}benzoyl)azepane

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E760-0912

Molecular Formula

C21H24N4O (C21 H24 N4 O)

Compound Name

1-(4-{2-ethyl-3H-imidazo[4,5-b]pyridin-3-yl}benzoyl)azepane

IUPAC name

1-(4-{2-ethyl-3H-imidazo[45-b]pyridin-3-yl}benzoyl)azepane

SMILES

CCc1nc2cccnc2n1-c(cc1)ccc1C(N1CCCCCC1)=O

InChI

InChI=1S/C21H24N4O/c1-2-19-23-18-8-7-13-22-20(18)25(19)17-11-9-16(10-12-17)21(26)24-14-5-3-4-6-15-24/h7-13H,2-6,14-15H2,1H3

InChI Key

RGEUKFHGDVFHBK-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14916566

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

348.45

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

3.348

Distribution Coefficient, logD

3.347

Water Solubility, LogSw

-3.33

Polar Surface Area

38.773

Acid Dissociation Constant (pKa)

27.87

Base Dissociation Constant (pKb)

4.66

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

38.10

E760-0912 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

CNS Targets (44014 compounds)

Cardiovascular Library (22201 compounds)

GPCR Targeted Library (31838 compounds)

Purinergic Library (3321 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Cardiovascular
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Nervous system
  • Cardiovascular
  • Metabolic
Targets:
  • GPCR
  • GPCR
  • Ion Channels
Mechanism of action:
  • Receptor's ligands
  • Receptor's ligands

References: we are preparing a list of scientific research reports with E760-0912 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E760-0912?
Check Price and Availability of E760-0912, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E760-0912 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E760-0912
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E760-0912
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E760-0912 available by request