E760-1152 Screening compound: N-[3-(4-ethylpiperazin-1-yl)propyl]-4-{2-phenyl-3H-imidazo[4,5-b]pyridin-3-yl}benzamide

E760-1152 Screening compound: N-[3-(4-ethylpiperazin-1-yl)propyl]-4-{2-phenyl-3H-imidazo[4,5-b]pyridin-3-yl}benzamide
E760-1152 Screening compound: N-[3-(4-ethylpiperazin-1-yl)propyl]-4-{2-phenyl-3H-imidazo[4,5-b]pyridin-3-yl}benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E760-1152
N-[3-(4-ethylpiperazin-1-yl)propyl]-4-{2-phenyl-3H-imidazo[4,5-b]pyridin-3-yl}benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E760-1152

Molecular Formula

C28H32N6O (C28 H32 N6 O)

Compound Name

N-[3-(4-ethylpiperazin-1-yl)propyl]-4-{2-phenyl-3H-imidazo[4,5-b]pyridin-3-yl}benzamide

IUPAC name

N-[3-(4-ethylpiperazin-1-yl)propyl]-4-{2-phenyl-3H-imidazo[45-b]pyridin-3-yl}benzamide

SMILES

CCN1CCN(CCCNC(c(cc2)ccc2-n2c(-c3ccccc3)nc3cccnc23)=O)CC1

InChI

InChI=1S/C28H32N6O/c1-2-32-18-20-33(21-19-32)17-7-16-30-28(35)23-11-13-24(14-12-23)34-26(22-8-4-3-5-9-22)31-25-10-6-15-29-27(25)34/h3-6,8-15H,2,7,16-21H2,1H3,(H,30,35)

InChI Key

LVIKHGUKCSUVFK-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14916593

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

468.6

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.079

Distribution Coefficient, logD

2.131

Water Solubility, LogSw

-3.17

Polar Surface Area

52.320

Acid Dissociation Constant (pKa)

14.01

Base Dissociation Constant (pKb)

8.30

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

32.10

E760-1152 in Drug Discovery

Included in Screening Libraries

GPCR Targeted Library (31838 compounds)

Neurotransmitter Transporter Inhibitors Library (11024 compounds)

PI3K-Targeted Library (17255 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Nervous system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • GPCR
  • GPCR
  • Ion Channels
  • Kinases
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with E760-1152 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E760-1152?
Check Price and Availability of E760-1152, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E760-1152 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E760-1152
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E760-1152
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E760-1152 available by request