E760-1242 Screening compound: 1-ethyl-4-(4-{2-phenyl-3H-imidazo[4,5-b]pyridin-3-yl}benzoyl)piperazine

E760-1242 Screening compound: 1-ethyl-4-(4-{2-phenyl-3H-imidazo[4,5-b]pyridin-3-yl}benzoyl)piperazine
E760-1242 Screening compound: 1-ethyl-4-(4-{2-phenyl-3H-imidazo[4,5-b]pyridin-3-yl}benzoyl)piperazine alternative view

Chemical Structure Depiction of ChemDiv screening compound E760-1242
1-ethyl-4-(4-{2-phenyl-3H-imidazo[4,5-b]pyridin-3-yl}benzoyl)piperazine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E760-1242

Molecular Formula

C25H25N5O (C25 H25 N5 O)

Compound Name

1-ethyl-4-(4-{2-phenyl-3H-imidazo[4,5-b]pyridin-3-yl}benzoyl)piperazine

IUPAC name

1-ethyl-4-(4-{2-phenyl-3H-imidazo[45-b]pyridin-3-yl}benzoyl)piperazine

SMILES

CCN(CC1)CCN1C(c(cc1)ccc1-n1c(-c2ccccc2)nc2cccnc12)=O

InChI

InChI=1S/C25H25N5O/c1-2-28-15-17-29(18-16-28)25(31)20-10-12-21(13-11-20)30-23(19-7-4-3-5-8-19)27-22-9-6-14-26-24(22)30/h3-14H,2,15-18H2,1H3

InChI Key

RURXQRPHKWGLND-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14916604

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

411.51

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.204

Distribution Coefficient, logD

3.027

Water Solubility, LogSw

-3.08

Polar Surface Area

40.731

Acid Dissociation Constant (pKa)

28.84

Base Dissociation Constant (pKb)

7.10

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

24.00

E760-1242 in Drug Discovery

Included in Screening Libraries

CNS Targets (44014 compounds)

Neurotransmitter Transporter Inhibitors Library (11024 compounds)

PI3K-Targeted Library (17255 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Purinergic Library (3321 compounds)

Epigenetics Focused Set (26518 compounds)

Ion Channels Focused Library (26372 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Nervous system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
  • Nervous system
  • Cardiovascular
  • Metabolic
  • Nervous system
  • Cardiovascular
Targets:
  • GPCR
  • Ion Channels
  • Kinases
  • Kinases
  • GPCR
  • Ion Channels
  • Ion Channels
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with E760-1242 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E760-1242?
Check Price and Availability of E760-1242, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E760-1242 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E760-1242
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E760-1242
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E760-1242 available by request