E760-4957 Screening compound: 1-(3-{3H-imidazo[4,5-b]pyridin-3-yl}benzoyl)-4-phenylpiperazine

E760-4957 Screening compound: 1-(3-{3H-imidazo[4,5-b]pyridin-3-yl}benzoyl)-4-phenylpiperazine
E760-4957 Screening compound: 1-(3-{3H-imidazo[4,5-b]pyridin-3-yl}benzoyl)-4-phenylpiperazine alternative view

Chemical Structure Depiction of ChemDiv screening compound E760-4957
1-(3-{3H-imidazo[4,5-b]pyridin-3-yl}benzoyl)-4-phenylpiperazine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E760-4957

Molecular Formula

C23H21N5O (C23 H21 N5 O)

Compound Name

1-(3-{3H-imidazo[4,5-b]pyridin-3-yl}benzoyl)-4-phenylpiperazine

IUPAC name

1-(3-{3H-imidazo[45-b]pyridin-3-yl}benzoyl)-4-phenylpiperazine

SMILES

O=C(c1cc(-n2c3ncccc3nc2)ccc1)N(CC1)CCN1c1ccccc1

InChI

InChI=1S/C23H21N5O/c29-23(27-14-12-26(13-15-27)19-7-2-1-3-8-19)18-6-4-9-20(16-18)28-17-25-21-10-5-11-24-22(21)28/h1-11,16-17H,12-15H2

InChI Key

ZOBNPQUSTZKGSL-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14916751

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

383.45

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

2.600

Distribution Coefficient, logD

2.600

Water Solubility, LogSw

-2.80

Polar Surface Area

40.698

Acid Dissociation Constant (pKa)

28.39

Base Dissociation Constant (pKb)

3.65

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

17.40

E760-4957 in Drug Discovery

Included in Screening Libraries

C-Met Library (15277 compounds)

GPCR Targeted Library (31838 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Targeted Diversity Library (40567 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases
  • GPCR
  • Kinases
Mechanism of action:
  • Receptor's ligands
  • Receptor's ligands

References: we are preparing a list of scientific research reports with E760-4957 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E760-4957?
Check Price and Availability of E760-4957, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E760-4957 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E760-4957
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E760-4957
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E760-4957 available by request