E760-4966 Screening compound: 1-(2,5-dimethylphenyl)-4-(3-{3H-imidazo[4,5-b]pyridin-3-yl}benzoyl)piperazine

E760-4966 Screening compound: 1-(2,5-dimethylphenyl)-4-(3-{3H-imidazo[4,5-b]pyridin-3-yl}benzoyl)piperazine
E760-4966 Screening compound: 1-(2,5-dimethylphenyl)-4-(3-{3H-imidazo[4,5-b]pyridin-3-yl}benzoyl)piperazine alternative view

Chemical Structure Depiction of ChemDiv screening compound E760-4966
1-(2,5-dimethylphenyl)-4-(3-{3H-imidazo[4,5-b]pyridin-3-yl}benzoyl)piperazine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E760-4966

Molecular Formula

C25H25N5O (C25 H25 N5 O)

Compound Name

1-(2,5-dimethylphenyl)-4-(3-{3H-imidazo[4,5-b]pyridin-3-yl}benzoyl)piperazine

IUPAC name

1-(25-dimethylphenyl)-4-(3-{3H-imidazo[45-b]pyridin-3-yl}benzoyl)piperazine

SMILES

Cc1cc(N(CC2)CCN2C(c2cc(-n3c4ncccc4nc3)ccc2)=O)c(C)cc1

InChI

InChI=1S/C25H25N5O/c1-18-8-9-19(2)23(15-18)28-11-13-29(14-12-28)25(31)20-5-3-6-21(16-20)30-17-27-22-7-4-10-26-24(22)30/h3-10,15-17H,11-14H2,1-2H3

InChI Key

QZPRGTPCWKMJHR-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14916755

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

411.51

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.758

Distribution Coefficient, logD

3.758

Water Solubility, LogSw

-3.82

Polar Surface Area

40.397

Acid Dissociation Constant (pKa)

28.39

Base Dissociation Constant (pKb)

3.65

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

24.00

E760-4966 in Drug Discovery

Included in Screening Libraries

PPI Inhibitors Tripeptide Mimetics (23972 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Akt-Targeted Library (14764 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
Structure:
  • Mimetics
Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases
  • Kinases

References: we are preparing a list of scientific research reports with E760-4966 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E760-4966?
Check Price and Availability of E760-4966, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E760-4966 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E760-4966
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E760-4966
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E760-4966 available by request