E760-7736 Screening compound: ethyl 1-[4-chloro-3-(2-methyl-3H-imidazo[4,5-b]pyridin-3-yl)benzoyl]-3-piperidinecarboxylate

E760-7736 Screening compound: ethyl 1-[4-chloro-3-(2-methyl-3H-imidazo[4,5-b]pyridin-3-yl)benzoyl]-3-piperidinecarboxylate
E760-7736 Screening compound: ethyl 1-[4-chloro-3-(2-methyl-3H-imidazo[4,5-b]pyridin-3-yl)benzoyl]-3-piperidinecarboxylate alternative view

Chemical Structure Depiction of ChemDiv screening compound E760-7736
ethyl 1-[4-chloro-3-(2-methyl-3H-imidazo[4,5-b]pyridin-3-yl)benzoyl]-3-piperidinecarboxylate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E760-7736

Molecular Formula

C22H23ClN4O3 (C22 H23 ClN4 O3)

Compound Name

ethyl 1-[4-chloro-3-(2-methyl-3H-imidazo[4,5-b]pyridin-3-yl)benzoyl]-3-piperidinecarboxylate

IUPAC name

ethyl 1-(4-chloro-3-{2-methyl-3H-imidazo[45-b]pyridin-3-yl}benzoyl)piperidine-3-carboxylate

SMILES

CCOC(C(CCC1)CN1C(c(cc1)cc(-n2c3ncccc3nc2C)c1Cl)=O)=O

InChI

InChI=1S/C22H23ClN4O3/c1-3-30-22(29)16-6-5-11-26(13-16)21(28)15-8-9-17(23)19(12-15)27-14(2)25-18-7-4-10-24-20(18)27/h4,7-10,12,16H,3,5-6,11,13H2,1-2H3/t16-/m0/s1

InChI Key

TZFYYXUOIYCSHB-INIZCTEOSA-N

MDL Number (MFCD)

MFCD27601279

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

426.9

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.621

Distribution Coefficient, logD

2.621

Water Solubility, LogSw

-3.26

Polar Surface Area

58.629

Acid Dissociation Constant (pKa)

22.44

Base Dissociation Constant (pKb)

4.22

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

36.36

E760-7736 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with E760-7736 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E760-7736?
Check Price and Availability of E760-7736, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E760-7736 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E760-7736
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E760-7736
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E760-7736 available by request