E786-0467 Screening compound: N-[(4-chlorophenyl)methyl]-3-[(1-cyclopropanecarbonyl-2-methyl-2,3-dihydro-1H-indol-5-yl)sulfonyl]propanamide

E786-0467 Screening compound: N-[(4-chlorophenyl)methyl]-3-[(1-cyclopropanecarbonyl-2-methyl-2,3-dihydro-1H-indol-5-yl)sulfonyl]propanamide
E786-0467 Screening compound: N-[(4-chlorophenyl)methyl]-3-[(1-cyclopropanecarbonyl-2-methyl-2,3-dihydro-1H-indol-5-yl)sulfonyl]propanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E786-0467
N-[(4-chlorophenyl)methyl]-3-[(1-cyclopropanecarbonyl-2-methyl-2,3-dihydro-1H-indol-5-yl)sulfonyl]propanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E786-0467

Molecular Formula

C23H25ClN2O4S (C23 H25 ClN2 O4 S)

Compound Name

N-[(4-chlorophenyl)methyl]-3-[(1-cyclopropanecarbonyl-2-methyl-2,3-dihydro-1H-indol-5-yl)sulfonyl]propanamide

IUPAC name

N-[(4-chlorophenyl)methyl]-3-[(1-cyclopropanecarbonyl-2-methyl-23-dihydro-1H-indol-5-yl)sulfonyl]propanamide

SMILES

CC(C1)N(C(C2CC2)=O)c(cc2)c1cc2S(CCC(NCc(cc1)ccc1Cl)=O)(=O)=O

InChI

InChI=1S/C23H25ClN2O4S/c1-15-12-18-13-20(8-9-21(18)26(15)23(28)17-4-5-17)31(29,30)11-10-22(27)25-14-16-2-6-19(24)7-3-16/h2-3,6-9,13,15,17H,4-5,10-12,14H2,1H3,(H,25,27)/t15-/m1/s1

InChI Key

SYHYNGLYGRBBFV-OAHLLOKOSA-N

MDL Number (MFCD)

MFCD14918607

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

460.98

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.034

Distribution Coefficient, logD

3.034

Water Solubility, LogSw

-3.66

Polar Surface Area

68.615

Acid Dissociation Constant (pKa)

11.84

Base Dissociation Constant (pKb)

-2.30

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

39.10

E786-0467 in Drug Discovery

Included in Screening Libraries

CNS targets activity set (6557 compounds)

Human Kinases Annotated Library (2415 compounds)

Human Transcription Factors Annotated Library (5098 compounds)

Selective Target Activity Profiling Library (14702 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Included in 1.7M Stock Database

References: we are preparing a list of scientific research reports with E786-0467 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E786-0467?
Check Price and Availability of E786-0467, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E786-0467 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E786-0467
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E786-0467
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E786-0467 available by request