E851-1906 Screening compound: 6,7,8,9,10,11-HEXAHYDROCYCLOOCTA[E]PYRAZOLO[1,5-A]PYRIMIDIN-3-YL(4-PHENYLPIPERAZINO)METHANONE

E851-1906 Screening compound: 6,7,8,9,10,11-HEXAHYDROCYCLOOCTA[E]PYRAZOLO[1,5-A]PYRIMIDIN-3-YL(4-PHENYLPIPERAZINO)METHANONE
E851-1906 Screening compound: 6,7,8,9,10,11-HEXAHYDROCYCLOOCTA[E]PYRAZOLO[1,5-A]PYRIMIDIN-3-YL(4-PHENYLPIPERAZINO)METHANONE alternative view

Chemical Structure Depiction of ChemDiv screening compound E851-1906
6,7,8,9,10,11-HEXAHYDROCYCLOOCTA[E]PYRAZOLO[1,5-A]PYRIMIDIN-3-YL(4-PHENYLPIPERAZINO)METHANONE

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E851-1906

Molecular Formula

C23H27N5O (C23 H27 N5 O)

Compound Name

6,7,8,9,10,11-HEXAHYDROCYCLOOCTA[E]PYRAZOLO[1,5-A]PYRIMIDIN-3-YL(4-PHENYLPIPERAZINO)METHANONE

IUPAC name

n/a

SMILES

O=C(c1c2ncc(CCCCCC3)c3n2nc1)N(CC1)CCN1c1ccccc1

InChI

InChI=1S/C23H27N5O/c29-23(27-14-12-26(13-15-27)19-9-5-3-6-10-19)20-17-25-28-21-11-7-2-1-4-8-18(21)16-24-22(20)28/h3,5-6,9-10,16-17H,1-2,4,7-8,11-15H2

InChI Key

WEVRIHRKOWNBFD-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14921926

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

389.5

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.742

Distribution Coefficient, logD

3.742

Water Solubility, LogSw

-3.76

Polar Surface Area

42.641

Acid Dissociation Constant (pKa)

27.59

Base Dissociation Constant (pKb)

5.75

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

43.50

E851-1906 in Drug Discovery

Included in Screening Libraries

GPCR Targeted Library (31838 compounds)

Protein-Protein Interaction Library (218420 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands
  • PPI modulators
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with E851-1906 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E851-1906?
Check Price and Availability of E851-1906, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E851-1906 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E851-1906
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E851-1906
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E851-1906 available by request