E867-0277 Screening compound: N-{3-[(4-acetylphenyl)carbamoyl]phenyl}-1H,2H,3H-pyrido[2,3-b][1,4]thiazine-1-carboxamide

E867-0277 Screening compound: N-{3-[(4-acetylphenyl)carbamoyl]phenyl}-1H,2H,3H-pyrido[2,3-b][1,4]thiazine-1-carboxamide
E867-0277 Screening compound: N-{3-[(4-acetylphenyl)carbamoyl]phenyl}-1H,2H,3H-pyrido[2,3-b][1,4]thiazine-1-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E867-0277
N-{3-[(4-acetylphenyl)carbamoyl]phenyl}-1H,2H,3H-pyrido[2,3-b][1,4]thiazine-1-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E867-0277

Molecular Formula

C23H20N4O3S (C23 H20 N4 O3 S)

Compound Name

N-{3-[(4-acetylphenyl)carbamoyl]phenyl}-1H,2H,3H-pyrido[2,3-b][1,4]thiazine-1-carboxamide

IUPAC name

N-{3-[(4-acetylphenyl)carbamoyl]phenyl}-1H2H3H-pyrido[23-b][14]thiazine-1-carboxamide

SMILES

CC(c(cc1)ccc1NC(c1cccc(NC(N2c3cccnc3SCC2)=O)c1)=O)=O

InChI

InChI=1S/C23H20N4O3S/c1-15(28)16-7-9-18(10-8-16)25-21(29)17-4-2-5-19(14-17)26-23(30)27-12-13-31-22-20(27)6-3-11-24-22/h2-11,14H,12-13H2,1H3,(H,25,29)(H,26,30)

InChI Key

HJYUVPQBHUKQRA-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14924664

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

432.5

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.222

Distribution Coefficient, logD

3.213

Water Solubility, LogSw

-3.51

Polar Surface Area

72.342

Acid Dissociation Constant (pKa)

9.07

Base Dissociation Constant (pKb)

1.98

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

13.00

E867-0277 in Drug Discovery

Included in Screening Libraries

Selective Target Activity Profiling Library (14702 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Included in 1.7M Stock Database

References: we are preparing a list of scientific research reports with E867-0277 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E867-0277?
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What is the minimum amount of E867-0277 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E867-0277
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E867-0277
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E867-0277 available by request