E879-2526 Screening compound: N-benzyl-6-{4-[(4-chlorophenyl)methyl]piperazin-1-yl}-1,5-naphthyridine-2-carboxamide

E879-2526 Screening compound: N-benzyl-6-{4-[(4-chlorophenyl)methyl]piperazin-1-yl}-1,5-naphthyridine-2-carboxamide
E879-2526 Screening compound: N-benzyl-6-{4-[(4-chlorophenyl)methyl]piperazin-1-yl}-1,5-naphthyridine-2-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E879-2526
N-benzyl-6-{4-[(4-chlorophenyl)methyl]piperazin-1-yl}-1,5-naphthyridine-2-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E879-2526

Molecular Formula

C27H26ClN5O (C27 H26 ClN5 O)

Compound Name

N-benzyl-6-{4-[(4-chlorophenyl)methyl]piperazin-1-yl}-1,5-naphthyridine-2-carboxamide

IUPAC name

N-benzyl-6-{4-[(4-chlorophenyl)methyl]piperazin-1-yl}-15-naphthyridine-2-carboxamide

SMILES

O=C(c(nc1cc2)ccc1nc2N1CCN(Cc(cc2)ccc2Cl)CC1)NCc1ccccc1

InChI

InChI=1S/C27H26ClN5O/c28-22-8-6-21(7-9-22)19-32-14-16-33(17-15-32)26-13-12-23-24(31-26)10-11-25(30-23)27(34)29-18-20-4-2-1-3-5-20/h1-13H,14-19H2,(H,29,34)

InChI Key

FPJGZONYAYJBGS-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14925382

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

471.99

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

5.306

Distribution Coefficient, logD

5.273

Water Solubility, LogSw

-5.92

Polar Surface Area

48.041

Acid Dissociation Constant (pKa)

11.65

Base Dissociation Constant (pKb)

6.29

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

22.20

E879-2526 in Drug Discovery

Included in Screening Libraries

Anti-Inflammatory Library (24602 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Epigenetics Focused Set (26518 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Immune system
Agro:
  • Agro

References: we are preparing a list of scientific research reports with E879-2526 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E879-2526?
Check Price and Availability of E879-2526, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E879-2526 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E879-2526
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E879-2526
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E879-2526 available by request