E882-0369 Screening compound: 3-[(7-methyl-2,3-dioxo-1,2,3,4-tetrahydroquinoxalin-6-yl)sulfonyl]-N-(4-methylphenyl)propanamide

E882-0369 Screening compound: 3-[(7-methyl-2,3-dioxo-1,2,3,4-tetrahydroquinoxalin-6-yl)sulfonyl]-N-(4-methylphenyl)propanamide
E882-0369 Screening compound: 3-[(7-methyl-2,3-dioxo-1,2,3,4-tetrahydroquinoxalin-6-yl)sulfonyl]-N-(4-methylphenyl)propanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E882-0369
3-[(7-methyl-2,3-dioxo-1,2,3,4-tetrahydroquinoxalin-6-yl)sulfonyl]-N-(4-methylphenyl)propanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E882-0369

Molecular Formula

C19H19N3O5S (C19 H19 N3 O5 S)

Compound Name

3-[(7-methyl-2,3-dioxo-1,2,3,4-tetrahydroquinoxalin-6-yl)sulfonyl]-N-(4-methylphenyl)propanamide

IUPAC name

3-[(7-methyl-23-dioxo-1234-tetrahydroquinoxalin-6-yl)sulfonyl]-N-(4-methylphenyl)propanamide

SMILES

Cc(cc1)ccc1NC(CCS(c(cc1NC2=O)c(C)cc1NC2=O)(=O)=O)=O

InChI

InChI=1S/C19H19N3O5S/c1-11-3-5-13(6-4-11)20-17(23)7-8-28(26,27)16-10-15-14(9-12(16)2)21-18(24)19(25)22-15/h3-6,9-10H,7-8H2,1-2H3,(H,20,23)(H,21,24)(H,22,25)

InChI Key

AFMBMSBVBVWNCU-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14925471

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

401.44

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

3.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

1.538

Distribution Coefficient, logD

1.138

Water Solubility, LogSw

-2.35

Polar Surface Area

101.987

Acid Dissociation Constant (pKa)

7.22

Base Dissociation Constant (pKb)

-0.38

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

21.10

E882-0369 in Drug Discovery

Included in Screening Libraries

Antiviral Library (67538 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

DGK Inhibitors Library (10558 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Cancer
  • Digestive system
  • Hemic and lymphatic
  • Skin
  • Metabolic
  • Immune system
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with E882-0369 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E882-0369?
Check Price and Availability of E882-0369, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E882-0369 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E882-0369
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E882-0369
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E882-0369 available by request