E897-0574 Screening compound: 2-[3'-(3-chlorophenyl)-2,4'-dioxo-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidin]-1-yl]-N-cyclopentylacetamide

E897-0574 Screening compound: 2-[3'-(3-chlorophenyl)-2,4'-dioxo-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidin]-1-yl]-N-cyclopentylacetamide
E897-0574 Screening compound: 2-[3'-(3-chlorophenyl)-2,4'-dioxo-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidin]-1-yl]-N-cyclopentylacetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E897-0574
2-[3'-(3-chlorophenyl)-2,4'-dioxo-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidin]-1-yl]-N-cyclopentylacetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E897-0574

Molecular Formula

C23H22ClN3O3S (C23 H22 ClN3 O3 S)

Compound Name

2-[3'-(3-chlorophenyl)-2,4'-dioxo-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidin]-1-yl]-N-cyclopentylacetamide

IUPAC name

2-[3'-(3-chlorophenyl)-24'-dioxo-12-dihydrospiro[indole-32'-[13]thiazolidin]-1-yl]-N-cyclopentylacetamide

SMILES

O=C(CN(C(C1(N2c3cccc(Cl)c3)SCC2=O)=O)c2c1cccc2)NC1CCCC1

InChI

InChI=1S/C23H22ClN3O3S/c24-15-6-5-9-17(12-15)27-21(29)14-31-23(27)18-10-3-4-11-19(18)26(22(23)30)13-20(28)25-16-7-1-2-8-16/h3-6,9-12,16H,1-2,7-8,13-14H2,(H,25,28)/t23-/m0/s1

InChI Key

UMASVADAXQYVQE-QHCPKHFHSA-N

MDL Number (MFCD)

MFCD14926368

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

455.96

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.666

Distribution Coefficient, logD

3.666

Water Solubility, LogSw

-4.10

Polar Surface Area

55.598

Acid Dissociation Constant (pKa)

13.21

Base Dissociation Constant (pKb)

1.14

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

34.80

E897-0574 in Drug Discovery

Included in Screening Libraries

Protein-Protein Interaction Library (218420 compounds)

Spiro Library (21655 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Cyclic compounds
  • Cyclic compounds

References: we are preparing a list of scientific research reports with E897-0574 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E897-0574?
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What is the minimum amount of E897-0574 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E897-0574
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E897-0574
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E897-0574 available by request