E899-0271 Screening compound: N-[3-(2,6-dimethylpiperidin-1-yl)propyl]-3-(4-fluorophenyl)-[1,2]oxazolo[5,4-d]pyrimidin-4-amine

E899-0271 Screening compound: N-[3-(2,6-dimethylpiperidin-1-yl)propyl]-3-(4-fluorophenyl)-[1,2]oxazolo[5,4-d]pyrimidin-4-amine
E899-0271 Screening compound: N-[3-(2,6-dimethylpiperidin-1-yl)propyl]-3-(4-fluorophenyl)-[1,2]oxazolo[5,4-d]pyrimidin-4-amine alternative view

Chemical Structure Depiction of ChemDiv screening compound E899-0271
N-[3-(2,6-dimethylpiperidin-1-yl)propyl]-3-(4-fluorophenyl)-[1,2]oxazolo[5,4-d]pyrimidin-4-amine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E899-0271

Molecular Formula

C21H26FN5O (C21 H26 FN5 O)

Compound Name

N-[3-(2,6-dimethylpiperidin-1-yl)propyl]-3-(4-fluorophenyl)-[1,2]oxazolo[5,4-d]pyrimidin-4-amine

IUPAC name

N-[3-(26-dimethylpiperidin-1-yl)propyl]-3-(4-fluorophenyl)-[12]oxazolo[54-d]pyrimidin-4-amine

SMILES

CC1N(CCCNc2c(c(-c(cc3)ccc3F)no3)c3ncn2)C(C)CCC1

InChI

InChI=1S/C21H26FN5O/c1-14-5-3-6-15(2)27(14)12-4-11-23-20-18-19(16-7-9-17(22)10-8-16)26-28-21(18)25-13-24-20/h7-10,13-15H,3-6,11-12H2,1-2H3,(H,23,24,25)

InChI Key

OXFIEPRVTUOTDN-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14926743

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

383.47

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.843

Distribution Coefficient, logD

1.223

Water Solubility, LogSw

-4.16

Polar Surface Area

55.403

Acid Dissociation Constant (pKa)

18.99

Base Dissociation Constant (pKb)

10.02

Number of Chiral Centers

2.00

Percent sp3 carbon bonding

47.60

E899-0271 in Drug Discovery

Included in Screening Libraries

MCL1 Targeted Library (12200 compounds)

Akt-Targeted Library (14764 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with E899-0271 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E899-0271?
Check Price and Availability of E899-0271, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E899-0271 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E899-0271
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E899-0271
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E899-0271 available by request