E902-0229 Screening compound: 2-{8-methyl-4-oxo-3H,4H,5H-pyridazino[4,5-b]indol-3-yl}-N-(4-sulfamoylphenyl)acetamide

E902-0229 Screening compound: 2-{8-methyl-4-oxo-3H,4H,5H-pyridazino[4,5-b]indol-3-yl}-N-(4-sulfamoylphenyl)acetamide
E902-0229 Screening compound: 2-{8-methyl-4-oxo-3H,4H,5H-pyridazino[4,5-b]indol-3-yl}-N-(4-sulfamoylphenyl)acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E902-0229
2-{8-methyl-4-oxo-3H,4H,5H-pyridazino[4,5-b]indol-3-yl}-N-(4-sulfamoylphenyl)acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E902-0229

Molecular Formula

C19H17N5O4S (C19 H17 N5 O4 S)

Compound Name

2-{8-methyl-4-oxo-3H,4H,5H-pyridazino[4,5-b]indol-3-yl}-N-(4-sulfamoylphenyl)acetamide

IUPAC name

2-{8-methyl-4-oxo-3H4H5H-pyridazino[45-b]indol-3-yl}-N-(4-sulfamoylphenyl)acetamide

SMILES

Cc(cc1)cc2c1[nH]c1c2C=NN(CC(Nc(cc2)ccc2S(N)(=O)=O)=O)C1=O

InChI

InChI=1S/C19H17N5O4S/c1-11-2-7-16-14(8-11)15-9-21-24(19(26)18(15)23-16)10-17(25)22-12-3-5-13(6-4-12)29(20,27)28/h2-9,23H,10H2,1H3,(H,22,25)(H2,20,27,28)

InChI Key

GTYKYMQYUNYGSZ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14926933

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

411.44

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

4.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

1.086

Distribution Coefficient, logD

1.085

Water Solubility, LogSw

-2.46

Polar Surface Area

112.193

Acid Dissociation Constant (pKa)

10.01

Base Dissociation Constant (pKb)

-0.89

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

10.50

E902-0229 in Drug Discovery

Included in Screening Libraries

Protein-Protein Interaction Library (218420 compounds)

Carbonic Anhydrase II Library (4939 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with E902-0229 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E902-0229?
Check Price and Availability of E902-0229, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E902-0229 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E902-0229
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E902-0229
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E902-0229 available by request