E903-0186 Screening compound: 1-{[3-(3,4-dimethoxyphenyl)-1,2,4-oxadiazol-5-yl]methyl}-N-[2-(4-methylpiperazino)ethyl]-3-piperidinecarboxamide

E903-0186 Screening compound: 1-{[3-(3,4-dimethoxyphenyl)-1,2,4-oxadiazol-5-yl]methyl}-N-[2-(4-methylpiperazino)ethyl]-3-piperidinecarboxamide
E903-0186 Screening compound: 1-{[3-(3,4-dimethoxyphenyl)-1,2,4-oxadiazol-5-yl]methyl}-N-[2-(4-methylpiperazino)ethyl]-3-piperidinecarboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E903-0186
1-{[3-(3,4-dimethoxyphenyl)-1,2,4-oxadiazol-5-yl]methyl}-N-[2-(4-methylpiperazino)ethyl]-3-piperidinecarboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E903-0186

Molecular Formula

C24H36N6O4 (C24 H36 N6 O4)

Compound Name

1-{[3-(3,4-dimethoxyphenyl)-1,2,4-oxadiazol-5-yl]methyl}-N-[2-(4-methylpiperazino)ethyl]-3-piperidinecarboxamide

IUPAC name

1-{[3-(34-dimethoxyphenyl)-124-oxadiazol-5-yl]methyl}-N-[2-(4-methylpiperazin-1-yl)ethyl]piperidine-3-carboxamide

SMILES

CN1CCN(CCNC(C2CN(Cc3nc(-c(cc4)cc(OC)c4OC)no3)CCC2)=O)CC1

InChI

InChI=1S/C24H36N6O4/c1-28-11-13-29(14-12-28)10-8-25-24(31)19-5-4-9-30(16-19)17-22-26-23(27-34-22)18-6-7-20(32-2)21(15-18)33-3/h6-7,15,19H,4-5,8-14,16-17H2,1-3H3,(H,25,31)/t19-/m0/s1

InChI Key

RUNWBAXGLYPYJR-IBGZPJMESA-N

MDL Number (MFCD)

MFCD14926958

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

472.59

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

10.00

Number of Nitrogen and Oxygen Atoms

10

Partition Coefficient, logP

1.006

Distribution Coefficient, logD

0.339

Water Solubility, LogSw

-2.12

Polar Surface Area

82.222

Acid Dissociation Constant (pKa)

12.73

Base Dissociation Constant (pKb)

7.96

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

62.50

E903-0186 in Drug Discovery

Included in Screening Libraries

GPCR Targeted Library (31838 compounds)

MCE-18 Trends in Medicinal Chemistry (51288 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with E903-0186 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E903-0186?
Check Price and Availability of E903-0186, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E903-0186 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E903-0186
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E903-0186
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E903-0186 available by request