E907-0014 Screening compound: 1-[(3-methoxyphenyl)methyl]-3-[4-methyl-2-(4-methylpiperazin-1-yl)quinolin-6-yl]urea

E907-0014 Screening compound: 1-[(3-methoxyphenyl)methyl]-3-[4-methyl-2-(4-methylpiperazin-1-yl)quinolin-6-yl]urea
E907-0014 Screening compound: 1-[(3-methoxyphenyl)methyl]-3-[4-methyl-2-(4-methylpiperazin-1-yl)quinolin-6-yl]urea alternative view

Chemical Structure Depiction of ChemDiv screening compound E907-0014
1-[(3-methoxyphenyl)methyl]-3-[4-methyl-2-(4-methylpiperazin-1-yl)quinolin-6-yl]urea

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E907-0014

Molecular Formula

C24H29N5O2 (C24 H29 N5 O2)

Compound Name

1-[(3-methoxyphenyl)methyl]-3-[4-methyl-2-(4-methylpiperazin-1-yl)quinolin-6-yl]urea

IUPAC name

1-[(3-methoxyphenyl)methyl]-3-[4-methyl-2-(4-methylpiperazin-1-yl)quinolin-6-yl]urea

SMILES

Cc1c(cc(cc2)NC(NCc3cc(OC)ccc3)=O)c2nc(N2CCN(C)CC2)c1

InChI

InChI=1S/C24H29N5O2/c1-17-13-23(29-11-9-28(2)10-12-29)27-22-8-7-19(15-21(17)22)26-24(30)25-16-18-5-4-6-20(14-18)31-3/h4-8,13-15H,9-12,16H2,1-3H3,(H2,25,26,30)

InChI Key

HETLCTGYACENPA-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14927060

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

419.53

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.272

Distribution Coefficient, logD

3.702

Water Solubility, LogSw

-4.38

Polar Surface Area

56.131

Acid Dissociation Constant (pKa)

12.70

Base Dissociation Constant (pKb)

7.83

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

33.30

E907-0014 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

CNS Targets (44014 compounds)

Purinergic Library (3321 compounds)

SmartTM Library (51161 compounds)

Epigenetics Focused Set (26518 compounds)

Histone Deacetylases (HDAC) Targeted Library (9760 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Nervous system
  • Cardiovascular
  • Metabolic
  • Cancer
  • Nervous system
  • Hemic and lymphatic
  • Endocrine
  • Immune system
Targets:
  • GPCR
  • Ion Channels
Mechanism of action:
  • Receptor's ligands
  • Epigenetic

References: we are preparing a list of scientific research reports with E907-0014 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E907-0014?
Check Price and Availability of E907-0014, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E907-0014 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E907-0014
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E907-0014
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E907-0014 available by request