E922-1041 Screening compound: 1-(2,3-dimethylphenyl)-4-[1-(4-methoxyphenyl)-5-(piperidin-4-yl)-1H-pyrazole-4-carbonyl]piperazine

E922-1041 Screening compound: 1-(2,3-dimethylphenyl)-4-[1-(4-methoxyphenyl)-5-(piperidin-4-yl)-1H-pyrazole-4-carbonyl]piperazine
E922-1041 Screening compound: 1-(2,3-dimethylphenyl)-4-[1-(4-methoxyphenyl)-5-(piperidin-4-yl)-1H-pyrazole-4-carbonyl]piperazine alternative view

Chemical Structure Depiction of ChemDiv screening compound E922-1041
1-(2,3-dimethylphenyl)-4-[1-(4-methoxyphenyl)-5-(piperidin-4-yl)-1H-pyrazole-4-carbonyl]piperazine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E922-1041

Molecular Formula

C28H35N5O2 (C28 H35 N5 O2)

Compound Name

1-(2,3-dimethylphenyl)-4-[1-(4-methoxyphenyl)-5-(piperidin-4-yl)-1H-pyrazole-4-carbonyl]piperazine

IUPAC name

1-(23-dimethylphenyl)-4-[1-(4-methoxyphenyl)-5-(piperidin-4-yl)-1H-pyrazole-4-carbonyl]piperazine

SMILES

Cc1cccc(N(CC2)CCN2C(c2c(C3CCNCC3)n(-c(cc3)ccc3OC)nc2)=O)c1C

InChI

InChI=1S/C28H35N5O2/c1-20-5-4-6-26(21(20)2)31-15-17-32(18-16-31)28(34)25-19-30-33(23-7-9-24(35-3)10-8-23)27(25)22-11-13-29-14-12-22/h4-10,19,22,29H,11-18H2,1-3H3

InChI Key

JXMWXWNQDKODLO-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14928474

Chemical and Physical Properties

Saltdata

HCl

Molecular Weight

473.62

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.540

Distribution Coefficient, logD

0.059

Water Solubility, LogSw

-3.47

Polar Surface Area

52.366

Acid Dissociation Constant (pKa)

22.02

Base Dissociation Constant (pKb)

10.88

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

42.90

E922-1041 in Drug Discovery

Included in Screening Libraries

Serine Proteases Inhibitors Library (32732 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Targets:
  • Proteases

References: we are preparing a list of scientific research reports with E922-1041 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E922-1041?
Check Price and Availability of E922-1041, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E922-1041 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E922-1041
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E922-1041
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E922-1041 available by request