E922-1621 Screening compound: 1-[1-(3-fluorophenyl)-5-(piperidin-4-yl)-1H-pyrazole-4-carbonyl]-4-(pyridin-2-yl)piperazine

E922-1621 Screening compound: 1-[1-(3-fluorophenyl)-5-(piperidin-4-yl)-1H-pyrazole-4-carbonyl]-4-(pyridin-2-yl)piperazine
E922-1621 Screening compound: 1-[1-(3-fluorophenyl)-5-(piperidin-4-yl)-1H-pyrazole-4-carbonyl]-4-(pyridin-2-yl)piperazine alternative view

Chemical Structure Depiction of ChemDiv screening compound E922-1621
1-[1-(3-fluorophenyl)-5-(piperidin-4-yl)-1H-pyrazole-4-carbonyl]-4-(pyridin-2-yl)piperazine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E922-1621

Molecular Formula

C24H27FN6O (C24 H27 FN6 O)

Compound Name

1-[1-(3-fluorophenyl)-5-(piperidin-4-yl)-1H-pyrazole-4-carbonyl]-4-(pyridin-2-yl)piperazine

IUPAC name

1-[1-(3-fluorophenyl)-5-(piperidin-4-yl)-1H-pyrazole-4-carbonyl]-4-(pyridin-2-yl)piperazine

SMILES

O=C(c1c(C2CCNCC2)n(-c2cccc(F)c2)nc1)N(CC1)CCN1c1ncccc1

InChI

InChI=1S/C24H27FN6O/c25-19-4-3-5-20(16-19)31-23(18-7-10-26-11-8-18)21(17-28-31)24(32)30-14-12-29(13-15-30)22-6-1-2-9-27-22/h1-6,9,16-18,26H,7-8,10-15H2

InChI Key

OIZRDWPEQKLKOL-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14928584

Chemical and Physical Properties

Saltdata

HCl

Molecular Weight

434.52

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.172

Distribution Coefficient, logD

-1.309

Water Solubility, LogSw

-2.76

Polar Surface Area

53.634

Acid Dissociation Constant (pKa)

21.63

Base Dissociation Constant (pKb)

10.88

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

37.50

E922-1621 in Drug Discovery

Included in Screening Libraries

SmartTM Library (51161 compounds)

Akt-Targeted Library (14764 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with E922-1621 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E922-1621?
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What is the minimum amount of E922-1621 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E922-1621
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E922-1621
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E922-1621 available by request