E944-0451 Screening compound: 2-{[3-(4-fluorophenyl)-[1,2]oxazolo[5,4-d]pyrimidin-4-yl]amino}-2-methylpropan-1-ol

E944-0451 Screening compound: 2-{[3-(4-fluorophenyl)-[1,2]oxazolo[5,4-d]pyrimidin-4-yl]amino}-2-methylpropan-1-ol
E944-0451 Screening compound: 2-{[3-(4-fluorophenyl)-[1,2]oxazolo[5,4-d]pyrimidin-4-yl]amino}-2-methylpropan-1-ol alternative view

Chemical Structure Depiction of ChemDiv screening compound E944-0451
2-{[3-(4-fluorophenyl)-[1,2]oxazolo[5,4-d]pyrimidin-4-yl]amino}-2-methylpropan-1-ol

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E944-0451

Molecular Formula

C15H15FN4O2 (C15 H15 FN4 O2)

Compound Name

2-{[3-(4-fluorophenyl)-[1,2]oxazolo[5,4-d]pyrimidin-4-yl]amino}-2-methylpropan-1-ol

IUPAC name

2-{[3-(4-fluorophenyl)-[12]oxazolo[54-d]pyrimidin-4-yl]amino}-2-methylpropan-1-ol

SMILES

CC(C)(CO)Nc1c(c(-c(cc2)ccc2F)no2)c2ncn1

InChI

InChI=1S/C15H15FN4O2/c1-15(2,7-21)19-13-11-12(9-3-5-10(16)6-4-9)20-22-14(11)18-8-17-13/h3-6,8,21H,7H2,1-2H3,(H,17,18,19)

InChI Key

GAWMIWYFRBSHTD-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14929240

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

302.31

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

2.285

Distribution Coefficient, logD

2.285

Water Solubility, LogSw

-2.62

Polar Surface Area

69.701

Acid Dissociation Constant (pKa)

16.19

Base Dissociation Constant (pKb)

2.74

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

26.70

E944-0451 in Drug Discovery

Included in Screening Libraries

3D-Biodiversity Library (27607 compounds)

Angiogenesis library (14822 compounds)

Antifungal Library (16415 compounds)

Antiviral Annotated Library (21441 compounds)

Dark Chemical Matter Library (18430 compounds)

Protein-Protein Interaction Library (218420 compounds)

Adenosine Receptors Targeted Library (19896 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Chemokine Receptor-Targeted Library (18382 compounds)

Ion Channels Focused Library (26372 compounds)

Target Identification, Phenotypic Screening library (TIPS) (27612 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
  • Pool
Therapeutical areas:
  • Cancer
  • Infections
  • Immune system
  • animal
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Eye
  • Cardiovascular
  • Immune system
  • Nervous system
  • Cardiovascular
Agro:
  • Agro
Mechanism of action:
  • PPI modulators
  • Receptor's ligands
  • Receptor's ligands
Targets:
  • GPCR
  • Ion Channels

References: we are preparing a list of scientific research reports with E944-0451 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E944-0451?
Check Price and Availability of E944-0451, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E944-0451 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E944-0451
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E944-0451
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E944-0451 available by request