E947-0303 Screening compound: N-[3-(4-ethoxyphenyl)-1,2-oxazol-5-yl]-3,6-dimethyl-4-oxo-3H,4H-furo[2,3-d]pyrimidine-5-carboxamide

E947-0303 Screening compound: N-[3-(4-ethoxyphenyl)-1,2-oxazol-5-yl]-3,6-dimethyl-4-oxo-3H,4H-furo[2,3-d]pyrimidine-5-carboxamide
E947-0303 Screening compound: N-[3-(4-ethoxyphenyl)-1,2-oxazol-5-yl]-3,6-dimethyl-4-oxo-3H,4H-furo[2,3-d]pyrimidine-5-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E947-0303
N-[3-(4-ethoxyphenyl)-1,2-oxazol-5-yl]-3,6-dimethyl-4-oxo-3H,4H-furo[2,3-d]pyrimidine-5-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E947-0303

Molecular Formula

C20H18N4O5 (C20 H18 N4 O5)

Compound Name

N-[3-(4-ethoxyphenyl)-1,2-oxazol-5-yl]-3,6-dimethyl-4-oxo-3H,4H-furo[2,3-d]pyrimidine-5-carboxamide

IUPAC name

N-[3-(4-ethoxyphenyl)-12-oxazol-5-yl]-36-dimethyl-4-oxo-3H4H-furo[23-d]pyrimidine-5-carboxamide

SMILES

CCOc(cc1)ccc1-c1noc(NC(c2c(C)oc(N=CN3C)c2C3=O)=O)c1

InChI

InChI=1S/C20H18N4O5/c1-4-27-13-7-5-12(6-8-13)14-9-15(29-23-14)22-18(25)16-11(2)28-19-17(16)20(26)24(3)10-21-19/h5-10H,4H2,1-3H3,(H,22,25)

InChI Key

JZYDKKRFXZBTLS-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27093753

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

394.39

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

2.277

Distribution Coefficient, logD

2.268

Water Solubility, LogSw

-2.94

Polar Surface Area

86.204

Acid Dissociation Constant (pKa)

9.10

Base Dissociation Constant (pKb)

-1.02

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

20.00

E947-0303 in Drug Discovery

Included in Screening Libraries

Anti-Aging Library (44940 compounds)

Anticancer Library (62698 compounds)

PI3K-Targeted Library (17255 compounds)

Aurora A-B Kinases Targeted Library (9426 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Metabolic
  • Immune system
  • Cancer
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Cancer
  • Digestive system
  • Male
  • Female
  • Hemic and lymphatic
Mechanism of action:
  • Epigenetic
Targets:
  • Kinases
  • Kinases

References: we are preparing a list of scientific research reports with E947-0303 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E947-0303?
Check Price and Availability of E947-0303, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E947-0303 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E947-0303
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E947-0303
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E947-0303 available by request