E947-0409 Screening compound: ethyl 2-(2-{3,6-dimethyl-4-oxo-3H,4H-furo[2,3-d]pyrimidine-5-amido}-1,3-thiazol-4-yl)acetate

E947-0409 Screening compound: ethyl 2-(2-{3,6-dimethyl-4-oxo-3H,4H-furo[2,3-d]pyrimidine-5-amido}-1,3-thiazol-4-yl)acetate
E947-0409 Screening compound: ethyl 2-(2-{3,6-dimethyl-4-oxo-3H,4H-furo[2,3-d]pyrimidine-5-amido}-1,3-thiazol-4-yl)acetate alternative view

Chemical Structure Depiction of ChemDiv screening compound E947-0409
ethyl 2-(2-{3,6-dimethyl-4-oxo-3H,4H-furo[2,3-d]pyrimidine-5-amido}-1,3-thiazol-4-yl)acetate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E947-0409

Molecular Formula

C16H16N4O5S (C16 H16 N4 O5 S)

Compound Name

ethyl 2-(2-{3,6-dimethyl-4-oxo-3H,4H-furo[2,3-d]pyrimidine-5-amido}-1,3-thiazol-4-yl)acetate

IUPAC name

ethyl 2-(2-{36-dimethyl-4-oxo-3H4H-furo[23-d]pyrimidine-5-amido}-13-thiazol-4-yl)acetate

SMILES

CCOC(Cc1csc(NC(c2c(C)oc(N=CN3C)c2C3=O)=O)n1)=O

InChI

InChI=1S/C16H16N4O5S/c1-4-24-10(21)5-9-6-26-16(18-9)19-13(22)11-8(2)25-14-12(11)15(23)20(3)7-17-14/h6-7H,4-5H2,1-3H3,(H,18,19,22)

InChI Key

VVCBUHUEFSMZFZ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27093796

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

376.39

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

1.088

Distribution Coefficient, logD

0.983

Water Solubility, LogSw

-2.19

Polar Surface Area

87.500

Acid Dissociation Constant (pKa)

7.96

Base Dissociation Constant (pKb)

-0.94

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

31.30

E947-0409 in Drug Discovery

Included in Screening Libraries

PI3K-Targeted Library (17255 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with E947-0409 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E947-0409?
Check Price and Availability of E947-0409, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E947-0409 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E947-0409
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E947-0409
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E947-0409 available by request