E948-0618 Screening compound: N-(5-CHLOROPYRIDIN-2-YL)-6-METHYL-4-(MORPHOLIN-4-YL)FURO[2,3-D]PYRIMIDINE-5-CARBOXAMIDE

E948-0618 Screening compound: N-(5-CHLOROPYRIDIN-2-YL)-6-METHYL-4-(MORPHOLIN-4-YL)FURO[2,3-D]PYRIMIDINE-5-CARBOXAMIDE
E948-0618 Screening compound: N-(5-CHLOROPYRIDIN-2-YL)-6-METHYL-4-(MORPHOLIN-4-YL)FURO[2,3-D]PYRIMIDINE-5-CARBOXAMIDE alternative view

Chemical Structure Depiction of ChemDiv screening compound E948-0618
N-(5-CHLOROPYRIDIN-2-YL)-6-METHYL-4-(MORPHOLIN-4-YL)FURO[2,3-D]PYRIMIDINE-5-CARBOXAMIDE

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E948-0618

Molecular Formula

C17H16ClN5O3 (C17 H16 ClN5 O3)

Compound Name

N-(5-CHLOROPYRIDIN-2-YL)-6-METHYL-4-(MORPHOLIN-4-YL)FURO[2,3-D]PYRIMIDINE-5-CARBOXAMIDE

IUPAC name

n/a

SMILES

Cc1c(C(Nc(cc2)ncc2Cl)=O)c2c(N3CCOCC3)ncnc2o1

InChI

InChI=1S/C17H16ClN5O3/c1-10-13(16(24)22-12-3-2-11(18)8-19-12)14-15(20-9-21-17(14)26-10)23-4-6-25-7-5-23/h2-3,8-9H,4-7H2,1H3,(H,19,22,24)

InChI Key

KVDVUSUWPBYYPF-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14929955

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

373.8

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

3.207

Distribution Coefficient, logD

3.201

Water Solubility, LogSw

-3.98

Polar Surface Area

72.259

Acid Dissociation Constant (pKa)

9.25

Base Dissociation Constant (pKb)

1.56

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

29.40

E948-0618 in Drug Discovery

Included in Screening Libraries

Anti-Aging Library (44940 compounds)

Antifungal Library (16415 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Adenosine Receptors Targeted Library (19896 compounds)

Type II Kinase Inhibitors Library (6956 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Metabolic
  • Immune system
  • Infections
  • Immune system
  • animal
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Eye
  • Cardiovascular
  • Digestive system
  • Hemic and lymphatic
  • Endocrine
Mechanism of action:
  • Epigenetic
  • Receptor's ligands
Agro:
  • Agro
Targets:
  • Kinases
  • GPCR
  • Kinases

References: we are preparing a list of scientific research reports with E948-0618 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E948-0618?
Check Price and Availability of E948-0618, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E948-0618 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E948-0618
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E948-0618
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E948-0618 available by request