E948-0744 Screening compound: 1'-[6-methyl-4-(morpholin-4-yl)furo[2,3-d]pyrimidine-5-carbonyl]-[1,4'-bipiperidine]-4'-carboxamide

E948-0744 Screening compound: 1'-[6-methyl-4-(morpholin-4-yl)furo[2,3-d]pyrimidine-5-carbonyl]-[1,4'-bipiperidine]-4'-carboxamide
E948-0744 Screening compound: 1'-[6-methyl-4-(morpholin-4-yl)furo[2,3-d]pyrimidine-5-carbonyl]-[1,4'-bipiperidine]-4'-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E948-0744
1'-[6-methyl-4-(morpholin-4-yl)furo[2,3-d]pyrimidine-5-carbonyl]-[1,4'-bipiperidine]-4'-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E948-0744

Molecular Formula

C23H32N6O4 (C23 H32 N6 O4)

Compound Name

1'-[6-methyl-4-(morpholin-4-yl)furo[2,3-d]pyrimidine-5-carbonyl]-[1,4'-bipiperidine]-4'-carboxamide

IUPAC name

1'-[6-methyl-4-(morpholin-4-yl)furo[23-d]pyrimidine-5-carbonyl]-[14'-bipiperidine]-4'-carboxamide

SMILES

Cc1c(C(N(CC2)CCC2(C(N)=O)N2CCCCC2)=O)c2c(N3CCOCC3)ncnc2o1

InChI

InChI=1S/C23H32N6O4/c1-16-17(18-19(25-15-26-20(18)33-16)27-11-13-32-14-12-27)21(30)28-9-5-23(6-10-28,22(24)31)29-7-3-2-4-8-29/h15H,2-14H2,1H3,(H2,24,31)

InChI Key

HRGNXWUQNPJKOM-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14930004

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

456.55

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

10

Partition Coefficient, logP

1.379

Distribution Coefficient, logD

0.306

Water Solubility, LogSw

-1.52

Polar Surface Area

93.247

Acid Dissociation Constant (pKa)

14.52

Base Dissociation Constant (pKb)

8.44

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

65.20

E948-0744 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Adenosine Receptors Targeted Library (19896 compounds)

Akt-Targeted Library (14764 compounds)

Anti-HIV1 Library (19540 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Eye
  • Cardiovascular
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Antiviral
  • Infections
  • Immune system
Targets:
  • GPCR
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with E948-0744 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E948-0744?
Check Price and Availability of E948-0744, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E948-0744 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E948-0744
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E948-0744
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E948-0744 available by request