E973-0460 Screening compound: N-[3-(trifluoromethyl)phenyl]-[1,2,4]triazolo[4,3-c]quinazolin-5-amine

E973-0460 Screening compound: N-[3-(trifluoromethyl)phenyl]-[1,2,4]triazolo[4,3-c]quinazolin-5-amine
E973-0460 Screening compound: N-[3-(trifluoromethyl)phenyl]-[1,2,4]triazolo[4,3-c]quinazolin-5-amine alternative view

Chemical Structure Depiction of ChemDiv screening compound E973-0460
N-[3-(trifluoromethyl)phenyl]-[1,2,4]triazolo[4,3-c]quinazolin-5-amine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E973-0460

Molecular Formula

C16H10F3N5 (C16 H10 F3 N5)

Compound Name

N-[3-(trifluoromethyl)phenyl]-[1,2,4]triazolo[4,3-c]quinazolin-5-amine

IUPAC name

N-[3-(trifluoromethyl)phenyl]-[124]triazolo[43-c]quinazolin-5-amine

SMILES

FC(c1cc(Nc2nc(cccc3)c3c3nncn23)ccc1)(F)F

InChI

InChI=1S/C16H10F3N5/c17-16(18,19)10-4-3-5-11(8-10)21-15-22-13-7-2-1-6-12(13)14-23-20-9-24(14)15/h1-9H,(H,21,22)

InChI Key

RGHLJIUYLOQTIK-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14934028

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

329.28

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

3.955

Distribution Coefficient, logD

3.887

Water Solubility, LogSw

-4.41

Polar Surface Area

41.697

Acid Dissociation Constant (pKa)

16.21

Base Dissociation Constant (pKb)

6.63

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

6.30

E973-0460 in Drug Discovery

Included in Screening Libraries

Anti-Aging Library (44940 compounds)

Antifungal Library (16415 compounds)

Immunological Library (6760 compounds)

Indoleamine 2,3-dioxygenase 1 Focused Library (5816 compounds)

Ion Channels Focused Library (26372 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Metabolic
  • Immune system
  • Infections
  • Immune system
  • animal
  • Immune system
  • Cancer
  • Digestive system
  • Female
  • Hemic and lymphatic
  • Metabolic
  • Immune system
  • Nervous system
  • Cardiovascular
Mechanism of action:
  • Epigenetic
Agro:
  • Agro
Targets:
  • Others
  • Ion Channels

References: we are preparing a list of scientific research reports with E973-0460 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E973-0460?
Check Price and Availability of E973-0460, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E973-0460 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E973-0460
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E973-0460
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E973-0460 available by request