E973-0486 Screening compound: 5-[4-(4-fluorophenyl)piperazino][1,2,4]triazolo[4,3-c]quinazoline

E973-0486 Screening compound: 5-[4-(4-fluorophenyl)piperazino][1,2,4]triazolo[4,3-c]quinazoline
E973-0486 Screening compound: 5-[4-(4-fluorophenyl)piperazino][1,2,4]triazolo[4,3-c]quinazoline alternative view

Chemical Structure Depiction of ChemDiv screening compound E973-0486
5-[4-(4-fluorophenyl)piperazino][1,2,4]triazolo[4,3-c]quinazoline

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E973-0486

Molecular Formula

C19H17FN6 (C19 H17 FN6)

Compound Name

5-[4-(4-fluorophenyl)piperazino][1,2,4]triazolo[4,3-c]quinazoline

IUPAC name

1-(4-fluorophenyl)-4-{[124]triazolo[43-c]quinazolin-5-yl}piperazine

SMILES

Fc(cc1)ccc1N(CC1)CCN1c1nc(cccc2)c2c2nncn12

InChI

InChI=1S/C19H17FN6/c20-14-5-7-15(8-6-14)24-9-11-25(12-10-24)19-22-17-4-2-1-3-16(17)18-23-21-13-26(18)19/h1-8,13H,9-12H2

InChI Key

MBZRNRNWWZSONY-UHFFFAOYSA-N

MDL Number (MFCD)

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

348.38

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

2.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.155

Distribution Coefficient, logD

3.125

Water Solubility, LogSw

-2.94

Polar Surface Area

37.131

Acid Dissociation Constant (pKa)

20.66

Base Dissociation Constant (pKb)

6.26

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

21.05

E973-0486 in Drug Discovery

Included in Screening Libraries

Protein Kinases Inhibitors Library (36801 compounds)

Targeted Diversity Library (40567 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with E973-0486 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E973-0486?
Check Price and Availability of E973-0486, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E973-0486 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E973-0486
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E973-0486
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E973-0486 available by request