E975-1419 Screening compound: 1-{5H,6H,7H,8H,9H,10H-cyclohepta[b]indole-2-sulfonyl}piperidine

E975-1419 Screening compound: 1-{5H,6H,7H,8H,9H,10H-cyclohepta[b]indole-2-sulfonyl}piperidine
E975-1419 Screening compound: 1-{5H,6H,7H,8H,9H,10H-cyclohepta[b]indole-2-sulfonyl}piperidine alternative view

Chemical Structure Depiction of ChemDiv screening compound E975-1419
1-{5H,6H,7H,8H,9H,10H-cyclohepta[b]indole-2-sulfonyl}piperidine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E975-1419

Molecular Formula

C18H24N2O2S (C18 H24 N2 O2 S)

Compound Name

1-{5H,6H,7H,8H,9H,10H-cyclohepta[b]indole-2-sulfonyl}piperidine

IUPAC name

1-{5H6H7H8H9H10H-cyclohepta[b]indole-2-sulfonyl}piperidine

SMILES

O=S(c(cc1)cc2c1[nH]c1c2CCCCC1)(N1CCCCC1)=O

InChI

InChI=1S/C18H24N2O2S/c21-23(22,20-11-5-2-6-12-20)14-9-10-18-16(13-14)15-7-3-1-4-8-17(15)19-18/h9-10,13,19H,1-8,11-12H2

InChI Key

AOKBJGJKPORUFW-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14934263

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

332.47

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

2.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

3.592

Distribution Coefficient, logD

3.592

Water Solubility, LogSw

-3.99

Polar Surface Area

43.051

Acid Dissociation Constant (pKa)

18.51

Base Dissociation Constant (pKb)

-3.37

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

55.60

E975-1419 in Drug Discovery

Included in Screening Libraries

Allosteric Kinases Inhibitors Library (23117 compounds)

DGK Inhibitors Library (10558 compounds)

Protein-Protein Interaction Library (218420 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Female
  • Congenital
  • Skin
  • Cancer
  • Digestive system
  • Hemic and lymphatic
  • Skin
  • Metabolic
  • Immune system
Targets:
  • Kinases
  • Kinases
Mechanism of action:
  • PPI modulators
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with E975-1419 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E975-1419?
Check Price and Availability of E975-1419, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E975-1419 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E975-1419
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E975-1419
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E975-1419 available by request