E984-1367 Screening compound: ethyl 1-(4-{2-methyl-5-oxo-4H,5H,6H,7H-pyrazolo[1,5-a]pyrimidin-4-yl}butanoyl)piperidine-4-carboxylate

E984-1367 Screening compound: ethyl 1-(4-{2-methyl-5-oxo-4H,5H,6H,7H-pyrazolo[1,5-a]pyrimidin-4-yl}butanoyl)piperidine-4-carboxylate
E984-1367 Screening compound: ethyl 1-(4-{2-methyl-5-oxo-4H,5H,6H,7H-pyrazolo[1,5-a]pyrimidin-4-yl}butanoyl)piperidine-4-carboxylate alternative view

Chemical Structure Depiction of ChemDiv screening compound E984-1367
ethyl 1-(4-{2-methyl-5-oxo-4H,5H,6H,7H-pyrazolo[1,5-a]pyrimidin-4-yl}butanoyl)piperidine-4-carboxylate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E984-1367

Molecular Formula

C19H28N4O4 (C19 H28 N4 O4)

Compound Name

ethyl 1-(4-{2-methyl-5-oxo-4H,5H,6H,7H-pyrazolo[1,5-a]pyrimidin-4-yl}butanoyl)piperidine-4-carboxylate

IUPAC name

ethyl 1-(4-{2-methyl-5-oxo-4H5H6H7H-pyrazolo[15-a]pyrimidin-4-yl}butanoyl)piperidine-4-carboxylate

SMILES

CCOC(C(CC1)CCN1C(CCCN(c1cc(C)nn1CC1)C1=O)=O)=O

InChI

InChI=1S/C19H28N4O4/c1-3-27-19(26)15-6-10-21(11-7-15)17(24)5-4-9-22-16-13-14(2)20-23(16)12-8-18(22)25/h13,15H,3-12H2,1-2H3

InChI Key

ULCJMWIZKHJAMC-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14936031

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

376.46

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

0.419

Distribution Coefficient, logD

0.419

Water Solubility, LogSw

-0.87

Polar Surface Area

65.223

Acid Dissociation Constant (pKa)

22.67

Base Dissociation Constant (pKb)

1.22

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

68.40

E984-1367 in Drug Discovery

Included in Screening Libraries

GPCR Targeted Library (31838 compounds)

Protein-Protein Interaction Library (218420 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands
  • PPI modulators
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with E984-1367 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E984-1367?
Check Price and Availability of E984-1367, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E984-1367 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E984-1367
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E984-1367
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E984-1367 available by request