F043-0383 Screening compound: 5-methoxy-2-(4-methoxyphenyl)-N-[(pyridin-3-yl)methyl]-1-benzofuran-3-carboxamide

F043-0383 Screening compound: 5-methoxy-2-(4-methoxyphenyl)-N-[(pyridin-3-yl)methyl]-1-benzofuran-3-carboxamide
F043-0383 Screening compound: 5-methoxy-2-(4-methoxyphenyl)-N-[(pyridin-3-yl)methyl]-1-benzofuran-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound F043-0383
5-methoxy-2-(4-methoxyphenyl)-N-[(pyridin-3-yl)methyl]-1-benzofuran-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F043-0383

Molecular Formula

C23H20N2O4 (C23 H20 N2 O4)

Compound Name

5-methoxy-2-(4-methoxyphenyl)-N-[(pyridin-3-yl)methyl]-1-benzofuran-3-carboxamide

IUPAC name

5-methoxy-2-(4-methoxyphenyl)-N-[(pyridin-3-yl)methyl]-1-benzofuran-3-carboxamide

SMILES

COc(cc1)ccc1-c1c(C(NCc2cnccc2)=O)c(cc(cc2)OC)c2o1

InChI

InChI=1S/C23H20N2O4/c1-27-17-7-5-16(6-8-17)22-21(19-12-18(28-2)9-10-20(19)29-22)23(26)25-14-15-4-3-11-24-13-15/h3-13H,14H2,1-2H3,(H,25,26)

InChI Key

RCKQZKRDDBDLGN-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD09240258

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

388.42

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.921

Distribution Coefficient, logD

3.920

Water Solubility, LogSw

-4.09

Polar Surface Area

57.511

Acid Dissociation Constant (pKa)

16.38

Base Dissociation Constant (pKb)

3.76

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

13.00

F043-0383 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

CNS Targets (44014 compounds)

GPCR Targeted Library (31838 compounds)

Ion Channels Focused Library (26372 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Nervous system
  • Cardiovascular
Targets:
  • GPCR
  • Ion Channels
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with F043-0383 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F043-0383?
Check Price and Availability of F043-0383, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F043-0383 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F043-0383
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F043-0383
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F043-0383 available by request