F060-0066 Screening compound: 1-(2-methoxyphenyl)-4-[5-(pyridin-3-yl)-1,2-oxazole-3-carbonyl]piperazine

F060-0066 Screening compound: 1-(2-methoxyphenyl)-4-[5-(pyridin-3-yl)-1,2-oxazole-3-carbonyl]piperazine
F060-0066 Screening compound: 1-(2-methoxyphenyl)-4-[5-(pyridin-3-yl)-1,2-oxazole-3-carbonyl]piperazine alternative view

Chemical Structure Depiction of ChemDiv screening compound F060-0066
1-(2-methoxyphenyl)-4-[5-(pyridin-3-yl)-1,2-oxazole-3-carbonyl]piperazine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F060-0066

Molecular Formula

C20H20N4O3 (C20 H20 N4 O3)

Compound Name

1-(2-methoxyphenyl)-4-[5-(pyridin-3-yl)-1,2-oxazole-3-carbonyl]piperazine

IUPAC name

1-(2-methoxyphenyl)-4-[5-(pyridin-3-yl)-12-oxazole-3-carbonyl]piperazine

SMILES

COc(cccc1)c1N(CC1)CCN1C(c1noc(-c2cnccc2)c1)=O

InChI

InChI=1S/C20H20N4O3/c1-26-18-7-3-2-6-17(18)23-9-11-24(12-10-23)20(25)16-13-19(27-22-16)15-5-4-8-21-14-15/h2-8,13-14H,9-12H2,1H3

InChI Key

CMUSDBAGBVTFPE-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD16961136

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

364.4

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.339

Distribution Coefficient, logD

2.339

Water Solubility, LogSw

-2.26

Polar Surface Area

58.530

Acid Dissociation Constant (pKa)

28.47

Base Dissociation Constant (pKb)

3.83

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

25.00

F060-0066 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Ion Channels Focused Library (26372 compounds)

Peptidomimetic Library (37031 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
  • Nervous system
  • Cardiovascular
Targets:
  • Kinases
  • Ion Channels
Mechanism of action:
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with F060-0066 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F060-0066?
Check Price and Availability of F060-0066, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F060-0066 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F060-0066
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F060-0066
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F060-0066 available by request