F061-1024 Screening compound: 2-{4-[1-({5-[(1E)-2-(2-fluorophenyl)ethenyl]-3-methyl-1,2-oxazol-4-yl}sulfonyl)piperidine-3-carbonyl]piperazin-1-yl}pyrimidine

F061-1024 Screening compound: 2-{4-[1-({5-[(1E)-2-(2-fluorophenyl)ethenyl]-3-methyl-1,2-oxazol-4-yl}sulfonyl)piperidine-3-carbonyl]piperazin-1-yl}pyrimidine
F061-1024 Screening compound: 2-{4-[1-({5-[(1E)-2-(2-fluorophenyl)ethenyl]-3-methyl-1,2-oxazol-4-yl}sulfonyl)piperidine-3-carbonyl]piperazin-1-yl}pyrimidine alternative view

Chemical Structure Depiction of ChemDiv screening compound F061-1024
2-{4-[1-({5-[(1E)-2-(2-fluorophenyl)ethenyl]-3-methyl-1,2-oxazol-4-yl}sulfonyl)piperidine-3-carbonyl]piperazin-1-yl}pyrimidine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F061-1024

Molecular Formula

C26H29FN6O4S (C26 H29 FN6 O4 S)

Compound Name

2-{4-[1-({5-[(1E)-2-(2-fluorophenyl)ethenyl]-3-methyl-1,2-oxazol-4-yl}sulfonyl)piperidine-3-carbonyl]piperazin-1-yl}pyrimidine

IUPAC name

2-{4-[1-({5-[(1E)-2-(2-fluorophenyl)ethenyl]-3-methyl-12-oxazol-4-yl}sulfonyl)piperidine-3-carbonyl]piperazin-1-yl}pyrimidine

SMILES

Cc1noc(/C=C/c(cccc2)c2F)c1S(N(CCC1)CC1C(N(CC1)CCN1c1ncccn1)=O)(=O)=O

InChI

InChI=1S/C26H29FN6O4S/c1-19-24(23(37-30-19)10-9-20-6-2-3-8-22(20)27)38(35,36)33-13-4-7-21(18-33)25(34)31-14-16-32(17-15-31)26-28-11-5-12-29-26/h2-3,5-6,8-12,21H,4,7,13-18H2,1H3/t21-/m0/s1

InChI Key

ORBCZUCJRDJYKY-NRFANRHFSA-N

MDL Number (MFCD)

MFCD27097695

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

540.62

Hydrogen Bond Acceptors Count

11.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

10

Partition Coefficient, logP

2.868

Distribution Coefficient, logD

2.868

Water Solubility, LogSw

-3.11

Polar Surface Area

91.669

Acid Dissociation Constant (pKa)

21.15

Base Dissociation Constant (pKb)

2.67

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

38.50

F061-1024 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Akt-Targeted Library (14764 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with F061-1024 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F061-1024?
Check Price and Availability of F061-1024, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F061-1024 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F061-1024
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F061-1024
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F061-1024 available by request