F082-0378 Screening compound: 8-[5-methyl-3-(pyridin-2-yl)-1,2-oxazole-4-carbonyl]-1,4-dioxa-8-azaspiro[4.5]decane

F082-0378 Screening compound: 8-[5-methyl-3-(pyridin-2-yl)-1,2-oxazole-4-carbonyl]-1,4-dioxa-8-azaspiro[4.5]decane
F082-0378 Screening compound: 8-[5-methyl-3-(pyridin-2-yl)-1,2-oxazole-4-carbonyl]-1,4-dioxa-8-azaspiro[4.5]decane alternative view

Chemical Structure Depiction of ChemDiv screening compound F082-0378
8-[5-methyl-3-(pyridin-2-yl)-1,2-oxazole-4-carbonyl]-1,4-dioxa-8-azaspiro[4.5]decane

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F082-0378

Molecular Formula

C17H19N3O4 (C17 H19 N3 O4)

Compound Name

8-[5-methyl-3-(pyridin-2-yl)-1,2-oxazole-4-carbonyl]-1,4-dioxa-8-azaspiro[4.5]decane

IUPAC name

8-[5-methyl-3-(pyridin-2-yl)-12-oxazole-4-carbonyl]-14-dioxa-8-azaspiro[4.5]decane

SMILES

Cc1c(C(N(CC2)CCC22OCCO2)=O)c(-c2ncccc2)no1

InChI

InChI=1S/C17H19N3O4/c1-12-14(15(19-24-12)13-4-2-3-7-18-13)16(21)20-8-5-17(6-9-20)22-10-11-23-17/h2-4,7H,5-6,8-11H2,1H3

InChI Key

DAUOPDSHKFQSLE-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27100132

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

329.36

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

0.789

Distribution Coefficient, logD

0.788

Water Solubility, LogSw

-1.22

Polar Surface Area

62.332

Acid Dissociation Constant (pKa)

26.57

Base Dissociation Constant (pKb)

4.08

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

47.10

F082-0378 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Included in 1.7M Stock Database

References: we are preparing a list of scientific research reports with F082-0378 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F082-0378?
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What is the minimum amount of F082-0378 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F082-0378
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F082-0378
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F082-0378 available by request