F118-0154 Screening compound: N~1~-(4,6-dimethyl-2-pyrimidinyl)-2-[3-oxo-6-(piperidinocarbonyl)-2,3-dihydro-4H-1,4-benzoxazin-4-yl]acetamide

F118-0154 Screening compound: N~1~-(4,6-dimethyl-2-pyrimidinyl)-2-[3-oxo-6-(piperidinocarbonyl)-2,3-dihydro-4H-1,4-benzoxazin-4-yl]acetamide
F118-0154 Screening compound: N~1~-(4,6-dimethyl-2-pyrimidinyl)-2-[3-oxo-6-(piperidinocarbonyl)-2,3-dihydro-4H-1,4-benzoxazin-4-yl]acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound F118-0154
N~1~-(4,6-dimethyl-2-pyrimidinyl)-2-[3-oxo-6-(piperidinocarbonyl)-2,3-dihydro-4H-1,4-benzoxazin-4-yl]acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F118-0154

Molecular Formula

C22H25N5O4 (C22 H25 N5 O4)

Compound Name

N~1~-(4,6-dimethyl-2-pyrimidinyl)-2-[3-oxo-6-(piperidinocarbonyl)-2,3-dihydro-4H-1,4-benzoxazin-4-yl]acetamide

IUPAC name

n/a

SMILES

Cc1nc(NC(CN2c(cc(cc3)C(N4CCCCC4)=O)c3OCC2=O)=O)nc(C)c1

InChI

InChI=1S/C22H25N5O4/c1-14-10-15(2)24-22(23-14)25-19(28)12-27-17-11-16(6-7-18(17)31-13-20(27)29)21(30)26-8-4-3-5-9-26/h6-7,10-11H,3-5,8-9,12-13H2,1-2H3,(H,23,24,25,28)

InChI Key

BZCVBEQDMZLKLK-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27102619

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

423.47

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

1.034

Distribution Coefficient, logD

1.033

Water Solubility, LogSw

-2.25

Polar Surface Area

83.184

Acid Dissociation Constant (pKa)

9.92

Base Dissociation Constant (pKb)

0.31

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

40.90

F118-0154 in Drug Discovery

Included in Screening Libraries

GPCR Targeted Library (31838 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Targets:
  • GPCR
  • Others
Mechanism of action:
  • Receptor's ligands
  • Epigenetic

References: we are preparing a list of scientific research reports with F118-0154 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F118-0154?
Check Price and Availability of F118-0154, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F118-0154 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F118-0154
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F118-0154
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F118-0154 available by request