F142-0084 Screening compound: 6,7-dimethoxy-3-{5-oxo-5-[4-(pyridin-2-yl)piperazin-1-yl]pentyl}-1,2,3,4-tetrahydroquinazoline-2,4-dione

F142-0084 Screening compound: 6,7-dimethoxy-3-{5-oxo-5-[4-(pyridin-2-yl)piperazin-1-yl]pentyl}-1,2,3,4-tetrahydroquinazoline-2,4-dione
F142-0084 Screening compound: 6,7-dimethoxy-3-{5-oxo-5-[4-(pyridin-2-yl)piperazin-1-yl]pentyl}-1,2,3,4-tetrahydroquinazoline-2,4-dione alternative view

Chemical Structure Depiction of ChemDiv screening compound F142-0084
6,7-dimethoxy-3-{5-oxo-5-[4-(pyridin-2-yl)piperazin-1-yl]pentyl}-1,2,3,4-tetrahydroquinazoline-2,4-dione

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F142-0084

Molecular Formula

C24H29N5O5 (C24 H29 N5 O5)

Compound Name

6,7-dimethoxy-3-{5-oxo-5-[4-(pyridin-2-yl)piperazin-1-yl]pentyl}-1,2,3,4-tetrahydroquinazoline-2,4-dione

IUPAC name

67-dimethoxy-3-{5-oxo-5-[4-(pyridin-2-yl)piperazin-1-yl]pentyl}-1234-tetrahydroquinazoline-24-dione

SMILES

COc(c(OC)c1)cc(C(N2CCCCC(N(CC3)CCN3c3ncccc3)=O)=O)c1NC2=O

InChI

InChI=1S/C24H29N5O5/c1-33-19-15-17-18(16-20(19)34-2)26-24(32)29(23(17)31)10-6-4-8-22(30)28-13-11-27(12-14-28)21-7-3-5-9-25-21/h3,5,7,9,15-16H,4,6,8,10-14H2,1-2H3,(H,26,32)

InChI Key

UVUKAWQZKWDPQW-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD11994464

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

467.52

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

10

Partition Coefficient, logP

2.085

Distribution Coefficient, logD

2.060

Water Solubility, LogSw

-3.08

Polar Surface Area

83.884

Acid Dissociation Constant (pKa)

8.82

Base Dissociation Constant (pKb)

5.71

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

41.70

F142-0084 in Drug Discovery

Included in Screening Libraries

Angiogenesis library (14822 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

SmartTM Library (51161 compounds)

Targeted Diversity Library (40567 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with F142-0084 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F142-0084?
Check Price and Availability of F142-0084, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F142-0084 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F142-0084
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F142-0084
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F142-0084 available by request