F146-1226 Screening compound: 3-(4-methylphenyl)-N-({1-[(3-methylphenyl)methyl]piperidin-4-yl}methyl)cinnoline-4-carboxamide

F146-1226 Screening compound: 3-(4-methylphenyl)-N-({1-[(3-methylphenyl)methyl]piperidin-4-yl}methyl)cinnoline-4-carboxamide
F146-1226 Screening compound: 3-(4-methylphenyl)-N-({1-[(3-methylphenyl)methyl]piperidin-4-yl}methyl)cinnoline-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound F146-1226
3-(4-methylphenyl)-N-({1-[(3-methylphenyl)methyl]piperidin-4-yl}methyl)cinnoline-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F146-1226

Molecular Formula

C30H32N4O (C30 H32 N4 O)

Compound Name

3-(4-methylphenyl)-N-({1-[(3-methylphenyl)methyl]piperidin-4-yl}methyl)cinnoline-4-carboxamide

IUPAC name

3-(4-methylphenyl)-N-({1-[(3-methylphenyl)methyl]piperidin-4-yl}methyl)cinnoline-4-carboxamide

SMILES

Cc(cc1)ccc1-c1c(C(NCC2CCN(Cc3cc(C)ccc3)CC2)=O)c2ccccc2nn1

InChI

InChI=1S/C30H32N4O/c1-21-10-12-25(13-11-21)29-28(26-8-3-4-9-27(26)32-33-29)30(35)31-19-23-14-16-34(17-15-23)20-24-7-5-6-22(2)18-24/h3-13,18,23H,14-17,19-20H2,1-2H3,(H,31,35)

InChI Key

RMIZCDGSFQYACB-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14943205

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

464.61

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

5.341

Distribution Coefficient, logD

2.849

Water Solubility, LogSw

-5.72

Polar Surface Area

50.341

Acid Dissociation Constant (pKa)

15.01

Base Dissociation Constant (pKb)

9.89

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

30.00

F146-1226 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

CNS Targets (44014 compounds)

GPCR Targeted Library (31838 compounds)

MCL1 Targeted Library (12200 compounds)

Ion Channels Focused Library (26372 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Nervous system
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Nervous system
  • Cardiovascular
Targets:
  • GPCR
  • Ion Channels
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with F146-1226 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F146-1226?
Check Price and Availability of F146-1226, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F146-1226 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F146-1226
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F146-1226
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F146-1226 available by request