F147-0887 Screening compound: 2-{[4-(morpholin-4-yl)-1,2,5-thiadiazol-3-yl]oxy}-N-[2-(trifluoromethyl)phenyl]propanamide

F147-0887 Screening compound: 2-{[4-(morpholin-4-yl)-1,2,5-thiadiazol-3-yl]oxy}-N-[2-(trifluoromethyl)phenyl]propanamide
F147-0887 Screening compound: 2-{[4-(morpholin-4-yl)-1,2,5-thiadiazol-3-yl]oxy}-N-[2-(trifluoromethyl)phenyl]propanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound F147-0887
2-{[4-(morpholin-4-yl)-1,2,5-thiadiazol-3-yl]oxy}-N-[2-(trifluoromethyl)phenyl]propanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F147-0887

Molecular Formula

C16H17F3N4O3S (C16 H17 F3 N4 O3 S)

Compound Name

2-{[4-(morpholin-4-yl)-1,2,5-thiadiazol-3-yl]oxy}-N-[2-(trifluoromethyl)phenyl]propanamide

IUPAC name

2-{[4-(morpholin-4-yl)-125-thiadiazol-3-yl]oxy}-N-[2-(trifluoromethyl)phenyl]propanamide

SMILES

CC(C(Nc1c(C(F)(F)F)cccc1)=O)Oc1nsnc1N1CCOCC1

InChI

InChI=1S/C16H17F3N4O3S/c1-10(14(24)20-12-5-3-2-4-11(12)16(17,18)19)26-15-13(21-27-22-15)23-6-8-25-9-7-23/h2-5,10H,6-9H2,1H3,(H,20,24)/t10-/m0/s1

InChI Key

IBZHEBQZRAOAJR-JTQLQIEISA-N

MDL Number (MFCD)

MFCD14943437

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

402.4

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.728

Distribution Coefficient, logD

3.728

Water Solubility, LogSw

-3.98

Polar Surface Area

61.953

Acid Dissociation Constant (pKa)

12.20

Base Dissociation Constant (pKb)

-0.01

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

43.80

F147-0887 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

PI3K-Targeted Library (17255 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with F147-0887 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F147-0887?
Check Price and Availability of F147-0887, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F147-0887 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F147-0887
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F147-0887
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F147-0887 available by request