F154-0522 Screening compound: 4-[(2-{[(2-chloro-4-fluorophenyl)methyl]sulfanyl}-3H-imidazo[4,5-c]pyridin-3-yl)methyl]-N-cyclohexylbenzamide

F154-0522 Screening compound: 4-[(2-{[(2-chloro-4-fluorophenyl)methyl]sulfanyl}-3H-imidazo[4,5-c]pyridin-3-yl)methyl]-N-cyclohexylbenzamide
F154-0522 Screening compound: 4-[(2-{[(2-chloro-4-fluorophenyl)methyl]sulfanyl}-3H-imidazo[4,5-c]pyridin-3-yl)methyl]-N-cyclohexylbenzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound F154-0522
4-[(2-{[(2-chloro-4-fluorophenyl)methyl]sulfanyl}-3H-imidazo[4,5-c]pyridin-3-yl)methyl]-N-cyclohexylbenzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F154-0522

Molecular Formula

C27H26ClFN4OS (C27 H26 ClFN4 OS)

Compound Name

4-[(2-{[(2-chloro-4-fluorophenyl)methyl]sulfanyl}-3H-imidazo[4,5-c]pyridin-3-yl)methyl]-N-cyclohexylbenzamide

IUPAC name

4-[(2-{[(2-chloro-4-fluorophenyl)methyl]sulfanyl}-3H-imidazo[45-c]pyridin-3-yl)methyl]-N-cyclohexylbenzamide

SMILES

O=C(c1ccc(Cn2c(SCc(ccc(F)c3)c3Cl)nc3c2cncc3)cc1)NC1CCCCC1

InChI

InChI=1S/C27H26ClFN4OS/c28-23-14-21(29)11-10-20(23)17-35-27-32-24-12-13-30-15-25(24)33(27)16-18-6-8-19(9-7-18)26(34)31-22-4-2-1-3-5-22/h6-15,22H,1-5,16-17H2,(H,31,34)

InChI Key

LBGRPIDBXWPGIP-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14943658

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

509.05

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

6.571

Distribution Coefficient, logD

6.567

Water Solubility, LogSw

-6.49

Polar Surface Area

44.134

Acid Dissociation Constant (pKa)

14.07

Base Dissociation Constant (pKb)

5.26

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

29.60

F154-0522 in Drug Discovery

Included in Screening Libraries

GABA Library (7115 compounds)

Protein Tyrosine Phosphatase Non-receptor Type (PTPN) Targeted Library (32556 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Eye
  • Cancer
  • Nervous system
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Endocrine
Targets:
  • GPCR
  • Ion Channels
  • Phosphatases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with F154-0522 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F154-0522?
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What is the minimum amount of F154-0522 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F154-0522
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F154-0522
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F154-0522 available by request