F159-0211 Screening compound: 1-(4-bromophenyl)-3-[2-(diethylamino)-4-methylquinolin-6-yl]urea

F159-0211 Screening compound: 1-(4-bromophenyl)-3-[2-(diethylamino)-4-methylquinolin-6-yl]urea
F159-0211 Screening compound: 1-(4-bromophenyl)-3-[2-(diethylamino)-4-methylquinolin-6-yl]urea alternative view

Chemical Structure Depiction of ChemDiv screening compound F159-0211
1-(4-bromophenyl)-3-[2-(diethylamino)-4-methylquinolin-6-yl]urea

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F159-0211

Molecular Formula

C21H23BrN4O (C21 H23 BrN4 O)

Compound Name

1-(4-bromophenyl)-3-[2-(diethylamino)-4-methylquinolin-6-yl]urea

IUPAC name

1-(4-bromophenyl)-3-[2-(diethylamino)-4-methylquinolin-6-yl]urea

SMILES

CCN(CC)c1cc(C)c(cc(cc2)NC(Nc(cc3)ccc3Br)=O)c2n1

InChI

InChI=1S/C21H23BrN4O/c1-4-26(5-2)20-12-14(3)18-13-17(10-11-19(18)25-20)24-21(27)23-16-8-6-15(22)7-9-16/h6-13H,4-5H2,1-3H3,(H2,23,24,27)

InChI Key

IUPSBCUJQPBGLF-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14943861

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

427.34

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

6.702

Distribution Coefficient, logD

6.699

Water Solubility, LogSw

-5.69

Polar Surface Area

43.072

Acid Dissociation Constant (pKa)

11.62

Base Dissociation Constant (pKb)

5.07

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

23.80

F159-0211 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

CNS Targets (44014 compounds)

Targeted Diversity Library (40567 compounds)

Histone Deacetylases (HDAC) Targeted Library (9760 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Nervous system
  • Cancer
  • Nervous system
  • Hemic and lymphatic
  • Endocrine
  • Immune system
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with F159-0211 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F159-0211?
Check Price and Availability of F159-0211, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F159-0211 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F159-0211
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F159-0211
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F159-0211 available by request