F186-0400 Screening compound: butyl 4-{2-[2-(4-methoxybenzamido)-1,3-thiazol-4-yl]acetamido}benzoate

F186-0400 Screening compound: butyl 4-{2-[2-(4-methoxybenzamido)-1,3-thiazol-4-yl]acetamido}benzoate
F186-0400 Screening compound: butyl 4-{2-[2-(4-methoxybenzamido)-1,3-thiazol-4-yl]acetamido}benzoate alternative view

Chemical Structure Depiction of ChemDiv screening compound F186-0400
butyl 4-{2-[2-(4-methoxybenzamido)-1,3-thiazol-4-yl]acetamido}benzoate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F186-0400

Molecular Formula

C24H25N3O5S (C24 H25 N3 O5 S)

Compound Name

butyl 4-{2-[2-(4-methoxybenzamido)-1,3-thiazol-4-yl]acetamido}benzoate

IUPAC name

butyl 4-{2-[2-(4-methoxybenzamido)-13-thiazol-4-yl]acetamido}benzoate

SMILES

CCCCOC(c(cc1)ccc1NC(Cc1csc(NC(c(cc2)ccc2OC)=O)n1)=O)=O

InChI

InChI=1S/C24H25N3O5S/c1-3-4-13-32-23(30)17-5-9-18(10-6-17)25-21(28)14-19-15-33-24(26-19)27-22(29)16-7-11-20(31-2)12-8-16/h5-12,15H,3-4,13-14H2,1-2H3,(H,25,28)(H,26,27,29)

InChI Key

NLVOQMSORWRROU-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD08535330

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

467.55

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

13.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

5.308

Distribution Coefficient, logD

5.273

Water Solubility, LogSw

-5.16

Polar Surface Area

85.341

Acid Dissociation Constant (pKa)

8.48

Base Dissociation Constant (pKb)

-1.38

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

25.00

F186-0400 in Drug Discovery

Included in Screening Libraries

Allosteric Kinases Inhibitors Library (23117 compounds)

Protein-Protein Interaction Library (218420 compounds)

Regenerative Medicine Focused Library (23016 compounds)

Adenosine Receptors Targeted Library (19896 compounds)

Chemokine Receptor-Targeted Library (18382 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Female
  • Congenital
  • Skin
  • Musculoskeletal
  • Digestive system
  • Hemic and lymphatic
  • Cardiovascular
  • Skin
  • wounds
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Eye
  • Cardiovascular
  • Immune system
Targets:
  • Kinases
  • GPCR
Mechanism of action:
  • PPI modulators
  • Receptor's ligands
  • Receptor's ligands

References: we are preparing a list of scientific research reports with F186-0400 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F186-0400?
Check Price and Availability of F186-0400, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F186-0400 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F186-0400
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F186-0400
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F186-0400 available by request