F186-1142 Screening compound: 2-(2-acetamido-1,3-thiazol-4-yl)-N-[(thiophen-2-yl)methyl]acetamide

F186-1142 Screening compound: 2-(2-acetamido-1,3-thiazol-4-yl)-N-[(thiophen-2-yl)methyl]acetamide
F186-1142 Screening compound: 2-(2-acetamido-1,3-thiazol-4-yl)-N-[(thiophen-2-yl)methyl]acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound F186-1142
2-(2-acetamido-1,3-thiazol-4-yl)-N-[(thiophen-2-yl)methyl]acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F186-1142

Molecular Formula

C12H13N3O2S2 (C12 H13 N3 O2 S2)

Compound Name

2-(2-acetamido-1,3-thiazol-4-yl)-N-[(thiophen-2-yl)methyl]acetamide

IUPAC name

2-(2-acetamido-13-thiazol-4-yl)-N-[(thiophen-2-yl)methyl]acetamide

SMILES

CC(Nc1nc(CC(NCc2cccs2)=O)cs1)=O

InChI

InChI=1S/C12H13N3O2S2/c1-8(16)14-12-15-9(7-19-12)5-11(17)13-6-10-3-2-4-18-10/h2-4,7H,5-6H2,1H3,(H,13,17)(H,14,15,16)

InChI Key

LTKPAMIUUGTQDC-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD08535554

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

295.39

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

1.864

Distribution Coefficient, logD

1.863

Water Solubility, LogSw

-2.36

Polar Surface Area

59.260

Acid Dissociation Constant (pKa)

9.94

Base Dissociation Constant (pKb)

-1.46

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

25.00

F186-1142 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Targets:
  • Others
  • Proteases
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with F186-1142 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F186-1142?
Check Price and Availability of F186-1142, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F186-1142 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F186-1142
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F186-1142
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F186-1142 available by request