F259-0105 Screening compound: N-(2-benzamido-1,3-benzothiazol-6-yl)-5-chloro-1H-indole-2-carboxamide

F259-0105 Screening compound: N-(2-benzamido-1,3-benzothiazol-6-yl)-5-chloro-1H-indole-2-carboxamide
F259-0105 Screening compound: N-(2-benzamido-1,3-benzothiazol-6-yl)-5-chloro-1H-indole-2-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound F259-0105
N-(2-benzamido-1,3-benzothiazol-6-yl)-5-chloro-1H-indole-2-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F259-0105

Molecular Formula

C23H15ClN4O2S (C23 H15 ClN4 O2 S)

Compound Name

N-(2-benzamido-1,3-benzothiazol-6-yl)-5-chloro-1H-indole-2-carboxamide

IUPAC name

N-(2-benzamido-13-benzothiazol-6-yl)-5-chloro-1H-indole-2-carboxamide

SMILES

O=C(c1cc(cc(cc2)Cl)c2[nH]1)Nc(cc1)cc2c1nc(NC(c1ccccc1)=O)s2

InChI

InChI=1S/C23H15ClN4O2S/c24-15-6-8-17-14(10-15)11-19(26-17)22(30)25-16-7-9-18-20(12-16)31-23(27-18)28-21(29)13-4-2-1-3-5-13/h1-12,26H,(H,25,30)(H,27,28,29)

InChI Key

NCTRITFPQFQWSZ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14946441

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

446.92

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

3.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

6.134

Distribution Coefficient, logD

6.132

Water Solubility, LogSw

-6.39

Polar Surface Area

65.531

Acid Dissociation Constant (pKa)

9.62

Base Dissociation Constant (pKb)

0.09

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

0.00

F259-0105 in Drug Discovery

Included in Screening Libraries

Allosteric Kinases Inhibitors Library (23117 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

Aurora A-B Kinases Targeted Library (9426 compounds)

Histone Deacetylases (HDAC) Targeted Library (9760 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Female
  • Congenital
  • Skin
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
  • Cancer
  • Digestive system
  • Male
  • Female
  • Hemic and lymphatic
  • Cancer
  • Nervous system
  • Hemic and lymphatic
  • Endocrine
  • Immune system
Targets:
  • Kinases
  • Others
  • Proteases
  • Kinases
Mechanism of action:
  • Epigenetic
  • Epigenetic

References: we are preparing a list of scientific research reports with F259-0105 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F259-0105?
Check Price and Availability of F259-0105, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F259-0105 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F259-0105
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F259-0105
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F259-0105 available by request