F281-0137 Screening compound: N~1~-(2,1,3-benzothiadiazol-4-yl)-2-(3-oxo-2,3-dihydro-4H-1,4-benzoxazin-4-yl)butanamide

F281-0137 Screening compound: N~1~-(2,1,3-benzothiadiazol-4-yl)-2-(3-oxo-2,3-dihydro-4H-1,4-benzoxazin-4-yl)butanamide
F281-0137 Screening compound: N~1~-(2,1,3-benzothiadiazol-4-yl)-2-(3-oxo-2,3-dihydro-4H-1,4-benzoxazin-4-yl)butanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound F281-0137
N~1~-(2,1,3-benzothiadiazol-4-yl)-2-(3-oxo-2,3-dihydro-4H-1,4-benzoxazin-4-yl)butanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F281-0137

Molecular Formula

C18H16N4O3S (C18 H16 N4 O3 S)

Compound Name

N~1~-(2,1,3-benzothiadiazol-4-yl)-2-(3-oxo-2,3-dihydro-4H-1,4-benzoxazin-4-yl)butanamide

IUPAC name

n/a

SMILES

CCC(C(Nc1cccc2nsnc12)=O)N1c(cccc2)c2OCC1=O

InChI

InChI=1S/C18H16N4O3S/c1-2-13(22-14-8-3-4-9-15(14)25-10-16(22)23)18(24)19-11-6-5-7-12-17(11)21-26-20-12/h3-9,13H,2,10H2,1H3,(H,19,24)/t13-/m0/s1

InChI Key

FAJIBFJMDQFRQY-ZDUSSCGKSA-N

MDL Number (MFCD)

MFCD14947103

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

368.42

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.958

Distribution Coefficient, logD

2.957

Water Solubility, LogSw

-3.48

Polar Surface Area

66.611

Acid Dissociation Constant (pKa)

10.10

Base Dissociation Constant (pKb)

-1.33

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

22.20

F281-0137 in Drug Discovery

Included in Screening Libraries

Protein Arginine Methyltransferases Library (27925 compounds)

Targeted Diversity Library (40567 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Targets:
  • Others
Mechanism of action:
  • Epigenetic
Agro:
  • Agro

References: we are preparing a list of scientific research reports with F281-0137 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F281-0137?
Check Price and Availability of F281-0137, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F281-0137 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F281-0137
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F281-0137
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F281-0137 available by request