F293-0460 Screening compound: 5-{[(3-chloro-2-methylphenyl)sulfonyl]amino}-2-(1-pyrrolidinyl)nicotinic acid

F293-0460 Screening compound: 5-{[(3-chloro-2-methylphenyl)sulfonyl]amino}-2-(1-pyrrolidinyl)nicotinic acid
F293-0460 Screening compound: 5-{[(3-chloro-2-methylphenyl)sulfonyl]amino}-2-(1-pyrrolidinyl)nicotinic acid alternative view

Chemical Structure Depiction of ChemDiv screening compound F293-0460
5-{[(3-chloro-2-methylphenyl)sulfonyl]amino}-2-(1-pyrrolidinyl)nicotinic acid

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F293-0460

Molecular Formula

C17H18ClN3O4S (C17 H18 ClN3 O4 S)

Compound Name

5-{[(3-chloro-2-methylphenyl)sulfonyl]amino}-2-(1-pyrrolidinyl)nicotinic acid

IUPAC name

5-(3-chloro-2-methylbenzenesulfonamido)-2-(pyrrolidin-1-yl)pyridine-3-carboxylic acid

SMILES

Cc(c(S(Nc(cc1C(O)=O)cnc1N1CCCC1)(=O)=O)ccc1)c1Cl

InChI

InChI=1S/C17H18ClN3O4S/c1-11-14(18)5-4-6-15(11)26(24,25)20-12-9-13(17(22)23)16(19-10-12)21-7-2-3-8-21/h4-6,9-10,20H,2-3,7-8H2,1H3,(H,22,23)

InChI Key

OWWPOBMCZCXJAY-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27112686

Chemical and Physical Properties

Saltdata

CF3COOH

Molecular Weight

395.87

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.860

Distribution Coefficient, logD

2.253

Water Solubility, LogSw

-3.89

Polar Surface Area

82.185

Acid Dissociation Constant (pKa)

5.80

Base Dissociation Constant (pKb)

2.44

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

29.41

F293-0460 in Drug Discovery

Included in Screening Libraries

PI3K-Targeted Library (17255 compounds)

SH2 Library (10483 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Cancer
  • Endocrine
Targets:
  • Kinases
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with F293-0460 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F293-0460?
Check Price and Availability of F293-0460, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F293-0460 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F293-0460
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F293-0460
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F293-0460 available by request