F296-0187 Screening compound: 6-[benzyl(methyl)amino]-5-(2,4,6-trimethylbenzenesulfonamido)pyridine-3-carboxylic acid

F296-0187 Screening compound: 6-[benzyl(methyl)amino]-5-(2,4,6-trimethylbenzenesulfonamido)pyridine-3-carboxylic acid
F296-0187 Screening compound: 6-[benzyl(methyl)amino]-5-(2,4,6-trimethylbenzenesulfonamido)pyridine-3-carboxylic acid alternative view

Chemical Structure Depiction of ChemDiv screening compound F296-0187
6-[benzyl(methyl)amino]-5-(2,4,6-trimethylbenzenesulfonamido)pyridine-3-carboxylic acid

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F296-0187

Molecular Formula

C23H25N3O4S (C23 H25 N3 O4 S)

Compound Name

6-[benzyl(methyl)amino]-5-(2,4,6-trimethylbenzenesulfonamido)pyridine-3-carboxylic acid

IUPAC name

6-[benzyl(methyl)amino]-5-(246-trimethylbenzenesulfonamido)pyridine-3-carboxylic acid

SMILES

Cc(cc1C)cc(C)c1S(Nc1c(N(C)Cc2ccccc2)ncc(C(O)=O)c1)(=O)=O

InChI

InChI=1S/C23H25N3O4S/c1-15-10-16(2)21(17(3)11-15)31(29,30)25-20-12-19(23(27)28)13-24-22(20)26(4)14-18-8-6-5-7-9-18/h5-13,25H,14H2,1-4H3,(H,27,28)

InChI Key

JHDPMCDYWRTVKW-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27113853

Chemical and Physical Properties

Saltdata

CF3COOH

Molecular Weight

439.54

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

5.249

Distribution Coefficient, logD

1.058

Water Solubility, LogSw

-4.71

Polar Surface Area

80.623

Acid Dissociation Constant (pKa)

3.21

Base Dissociation Constant (pKb)

3.07

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

21.70

F296-0187 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Glucocorticoid receptors Library (4806 compounds)

PI3K-Targeted Library (17255 compounds)

SH2 Library (10483 compounds)

Type II Kinase Inhibitors Library (6956 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Nervous system
  • Hemic and lymphatic
  • Congenital
  • Metabolic
  • Endocrine
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Cancer
  • Endocrine
  • Digestive system
  • Hemic and lymphatic
  • Endocrine
Targets:
  • Nuclear receptors
  • Kinases
  • Kinases
Mechanism of action:
  • Receptor's ligands
  • PPI modulators

References: we are preparing a list of scientific research reports with F296-0187 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F296-0187?
Check Price and Availability of F296-0187, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F296-0187 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F296-0187
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F296-0187
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F296-0187 available by request